Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 3/20 | 0.40 |
| ▸ | RXRB | P28702 | 3/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20732321 | 0.92 | ALDH1A1 (0.45) | HDAC3HDAC1HDAC2NCOR2ALDH1A1 | |
| SCHEMBL7066900 | 0.83 | SRD5A2 (0.38) | HDAC3HDAC1HDAC2NCOR2MAPT | |
| SCHEMBL18921972 | 0.78 | NPSR1 (0.44) | HDAC3HDAC1HDAC2NCOR2ALDH1A1 | |
| SCHEMBL30878162 | 0.78 | POLB (0.47) | ALDH1A1MAPTHPGDSYKL3MBTL1 | |
| SCHEMBL30307663 | 0.78 | POLB (0.47) | ALDH1A1MAPTHPGDSYKL3MBTL1 | |
| SCHEMBL2499502 | 0.78 | POLB (0.47) | ALDH1A1MAPTHPGDSYKL3MBTL1 | |
| SCHEMBL57636 | 0.77 | MMP13 (0.40) | HDAC3HDAC1HDAC2KMT2A | |
| SCHEMBL88675 | 0.77 | MMP13 (0.40) | HDAC3HDAC1HDAC2KMT2A | |
| SCHEMBL5981030 | 0.75 | MMP13 (0.40) | ALDH1A1MAPTL3MBTL1POLBKMT2A | |
| SCHEMBL88460 | 0.75 | MMP13 (0.40) | ALDH1A1MAPTL3MBTL1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113412271-A | Hamiltrin derivatives having cysteine residue | 大日本住友制药株式会社 | 2021-09-17 | — | — | CN | disclosed |
| CN-111032676-A | Antibody drug complex comprising a hemiasterlin derivative | 大日本住友制药株式会社 | 2020-04-17 | — | — | CN | disclosed |