Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.43 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.43 |
| ▸ | BMP1 | P13497 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15822646 | 0.86 | KMT2A (0.48) | ECE1KMT2ANOD1FOLH1CA2 | |
| SCHEMBL15822647 | 0.86 | KMT2A (0.48) | ECE1KMT2ANOD1FOLH1CA2 | |
| SCHEMBL27396231 | 0.85 | NOD1 (0.47) | ECE1KMT2ANOD1FOLH1CA2 | |
| SCHEMBL8430995 | 0.85 | NOD1 (0.47) | ECE1KMT2ANOD1FOLH1CA2 | |
| SCHEMBL27396227 | 0.85 | NOD1 (0.47) | ECE1KMT2ANOD1FOLH1CA2 | |
| SCHEMBL8429139 | 0.85 | NOD1 (0.47) | ECE1KMT2ANOD1FOLH1CA2 | |
| SCHEMBL6600219 | 0.85 | NOD1 (0.47) | ECE1KMT2ANOD1FOLH1CA2 | |
| SCHEMBL2492939 | 0.85 | NOD1 (0.47) | ECE1KMT2ANOD1FOLH1CA2 | |
| SCHEMBL4221433 | 0.85 | NOD1 (0.47) | ECE1KMT2ANOD1FOLH1CA2 | |
| Alanyl Glutamine SCHEMBL4274839 | 0.84 | NOD1 (0.59) | ECE1KMT2ANOD1FOLH1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669106-B2 | Conjugate of monomethyl auristatin F and trastuzumab and its use for the treatment of cancer | PIERRE FABRE MEDICAMENT (FR) | 2017-06-06 | — | — | US | disclosed |