SCHEMBL18922710

SCHEMBL18922710

CCOC1CC2COCC(C1)N2C

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR3A P46098 18/20 0.35
HSD11B1 P28845 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19068162 0.81 CYP2C9 (0.44) HTR3AHSD11B1
SCHEMBL2627864 0.78 CHRM1 (0.40) HTR3AHSD11B1
SCHEMBL19969985 0.77 HTR3A (0.34) HTR3A
SCHEMBL15444674 0.77 HTR3A (0.35) HTR3A
SCHEMBL19969876 0.76 HTR3A (0.33) HTR3A
SCHEMBL15440801 0.75 SLC6A3 (0.37) HTR3A
SCHEMBL14232024 0.75
SCHEMBL15030963 0.75
SCHEMBL19969959 0.73 HTR3A (0.32) HTR3A
SCHEMBL733705 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9670229-B2 5-HT3 receptor antagonists TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-06-06 US disclosed