Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2605612 | 0.91 | SMN1; SMN2 (0.43) | MEN1KMT2ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL18922729 | 0.83 | SMN1; SMN2 (0.38) | MEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL25984078 | 0.82 | TSHR (0.40) | MEN1KMT2AEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL15745539 | 0.80 | RIPK1 (0.38) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15255244 | 0.80 | MEN1 (0.52) | THRBMEN1KMT2AEPHX2SMN1; SMN2 | |
| SCHEMBL18199506 | 0.80 | MEN1 (0.52) | THRBMEN1KMT2AEPHX2SMN1; SMN2 | |
| SCHEMBL23518687 | 0.78 | MEN1 (0.46) | THRBMEN1KMT2AEPHX2SMN1; SMN2 | |
| SCHEMBL25516086 | 0.78 | MEN1 (0.46) | THRBMEN1KMT2AEPHX2SMN1; SMN2 | |
| SCHEMBL7559812 | 0.78 | MEN1 (0.46) | THRBMEN1KMT2AEPHX2SMN1; SMN2 | |
| SCHEMBL9735108 | 0.77 | EPHX2 (0.44) | THRBMEN1KMT2AEPHX2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9668944-B2 | Dental composition | DENTSPLY INTERNATIONAL INC. (US) | 2017-06-06 | — | — | US | disclosed |