Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 6/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA4 | P22748 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.30 |
| ▸ | ENO1 | P06733 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2605612 | 0.91 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2ACA2CA12 | |
| SCHEMBL18922728 | 0.83 | THRB (0.41) | SMN1; SMN2MEN1KMT2AHSD17B10 | |
| SCHEMBL25984078 | 0.82 | TSHR (0.40) | SMN1; SMN2MEN1KMT2AALOX15HSD17B10 | |
| SCHEMBL321616 | 0.82 | MEN1 (0.41) | SMN1; SMN2MEN1KMT2ACA2CA12 | |
| SCHEMBL22368126 | 0.82 | MEN1 (0.41) | SMN1; SMN2MEN1KMT2ACA2CA12 | |
| SCHEMBL10065799 | 0.81 | ALOX15 (0.39) | MEN1KMT2AALOX15HSD17B10 | |
| SCHEMBL19172671 | 0.80 | CA2 (0.49) | SMN1; SMN2MEN1KMT2ACA2CA12 | |
| SCHEMBL28672982 | 0.80 | MEN1 (0.38) | SMN1; SMN2MEN1KMT2ACA2CA12 | |
| SCHEMBL24040332 | 0.78 | MEN1 (0.41) | SMN1; SMN2MEN1KMT2ACA2CA12 | |
| SCHEMBL21415394 | 0.78 | CA2 (0.44) | SMN1; SMN2MEN1KMT2ACA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9668944-B2 | Dental composition | DENTSPLY INTERNATIONAL INC. (US) | 2017-06-06 | — | — | US | disclosed |