Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27895270 | 0.98 | HDAC4 (0.45) | HDAC4HDAC8KDM4EALDH1A1ALOX12 | |
| Hydrochloric Acid SCHEMBL4454669 | 0.95 | HDAC4 (0.44) | HDAC4HDAC8KDM4EALDH1A1ALOX12 | |
| SCHEMBL20591157 | 0.88 | KDM4E (0.39) | HDAC4HDAC8KDM4EALDH1A1ALOX12 | |
| SCHEMBL374780 | 0.81 | HDAC4 (0.56) | HDAC4HDAC8KDM4EALDH1A1ALOX12 | |
| Benzene SCHEMBL7084450 | 0.78 | HDAC4 (0.54) | HDAC4HDAC8KDM4EALDH1A1ALOX12 | |
| SCHEMBL11036540 | 0.78 | HDAC4 (0.54) | HDAC4HDAC8KDM4EALDH1A1ALOX12 | |
| Hydrochloric Acid SCHEMBL28429663 | 0.78 | HDAC4 (0.54) | HDAC4HDAC8KDM4EALDH1A1ALOX12 | |
| SCHEMBL31122172 | 0.78 | HDAC4 (0.54) | HDAC4HDAC8KDM4EALDH1A1ALOX12 | |
| Water SCHEMBL9322811 | 0.78 | HDAC4 (0.54) | HDAC4HDAC8KDM4EALDH1A1ALOX12 | |
| SCHEMBL19031518 | 0.78 | KDM4E (0.54) | HDAC4HDAC8KDM4EALDH1A1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365525-A1 | ANTIVIRAL COMPOUNDS | ENANTA PHARMACEUTICALS, INC. | 2023-11-16 | — | — | US | disclosed |
| US-20230371357-A1 | ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-11-16 | — | — | US | disclosed |
| US-20220280488-A1 | PHARMACEUTICALLY ACTIVE PYRAZOLO-PYRIDONE MODULATORS OF DCN1/2-MEDIATED CULLIN NEDDYLATION | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2022-09-08 | — | — | US | disclosed |
| CN-110003271-B | Process for producing aromatic compound | 住友化学株式会社 | 2022-05-03 | — | — | CN | disclosed |
| US-20210047287-A1 | NONPEPTIDE SOMATOSTATIN TYPE 5 RECEPTOR AGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2021-02-18 | — | — | US | disclosed |
| US-20200397774-A1 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | INCYTE HOLDINGS CORPORATION | 2020-12-24 | — | — | US | disclosed |
| CN-110003271-A | The preparation method of aromatic compound | 住友化学株式会社 | 2019-07-12 | — | — | CN | disclosed |
| US-20190055204-A1 | COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. | 2019-02-21 | — | — | US | disclosed |
| US-9670201-B2 | Methyl- and trifluoromethyl-substituted pyrrolopyridine modulators of RORC2 and methods of use thereof | PFIZER INC. (US) | 2017-06-06 | — | — | US | disclosed |
| CN-106083927-A | Phosphinyl amidine compound, metal complex, antigravity system and their oligomeric or purposes of olefin polymerization | 切弗朗菲利浦化学公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-1898304-A | Method for bonding polybutadiene molded article, polybutadiene composite molded article obtained by the method, medical member, and infusion device | JSR CORP (JP) | 2007-01-17 | — | — | CN | disclosed |
| CN-1223616-C | 1, 2-polybutadiene, thermoplastic elastomer composition and polymer composition | JSR CORP (JP) | 2005-10-19 | — | — | CN | disclosed |
| CN-1215068-C | Prepn process of 2,3,3',4'-diphenyl tetraformic dianhydride and its derivative | CHANGCHUN APPLIED CHEMISTRY (CN) | 2005-08-17 | — | — | CN | disclosed |
| CN-1583188-A | Medical member and medical instrument | JSR CORP (JP) | 2005-02-23 | — | — | CN | disclosed |
| CN-1189597-C | Preparation of biphenylyl tetra formicdianhydride and its derivative using electrochemical method | CHANGCHUN APPLIED CHEMISTRY (CN) | 2005-02-16 | — | — | CN | disclosed |
| CN-1511176-A | Oil extended 1,2-polybutadiene and method of manufacturing polybutadiene, and composition and formed product thereof | JSR株式会社 | 2004-07-07 | — | — | CN | disclosed |
| CN-1454221-A | 1, 2-polybutadiene, thermoplastic elastomer composition and polymer composition | JSR CORP (JP) | 2003-11-05 | — | — | CN | disclosed |
| CN-1436780-A | Prepn process of 2,3,3',4'-diphenyl tetraformic dianhydride and its derivative | CHANGCHUN APPLIED CHEMISTRY (CN) | 2003-08-20 | — | — | CN | disclosed |
| CN-1410598-A | Preparation of biphenylyl tetra formicdianhydride and its derivative using electrochemical method | CHANGCHUN APPLIED CHEMISTRY (CN) | 2003-04-16 | — | — | CN | disclosed |
| CN-1278834-A | gas phase polymerization of vinyl polybutadiene | UNION CARBIDE CHEM PLASTIC (US) | 2001-01-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220280488-A1 | PHARMACEUTICALLY ACTIVE PYRAZOLO-PYRIDONE MODULATORS OF DCN1/2-MEDIATED CULLIN NEDDYLATION | CUL1, CUL2, NEDD8 | HDAC4 667/4885HDAC8 739/4885KDM4E 2253/4885 |
| US-20200397774-A1 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | JAK1, JAK2, JAK3 | HDAC4 1067/4885HDAC8 1653/4885KDM4E 248/4885 |
| US-20230371357-A1 | ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE | L1CAM, CHRM1, FOXM1 | HDAC4 4574/4885HDAC8 4643/4885KDM4E 3285/4885 |
| US-20210047287-A1 | NONPEPTIDE SOMATOSTATIN TYPE 5 RECEPTOR AGONISTS AND USES THEREOF | SSTR5, SSTR4, SSTR3 | HDAC4 1310/4885HDAC8 1275/4885KDM4E 4514/4885 |
| US-20230365525-A1 | ANTIVIRAL COMPOUNDS | ACE, ZC3HAV1, SARS1 | HDAC4 1252/4885HDAC8 2434/4885KDM4E 1688/4885 |
| US-20190055204-A1 | COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF | GRM5, GRM2, GRM1 | HDAC4 747/4885HDAC8 682/4885KDM4E 2003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.