Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.76 |
| ▸ | POLA1 | P09884 | 1/20 | 0.76 |
| ▸ | POLD1 | P28340 | 1/20 | 0.76 |
| ▸ | TK1 | P04183 | 5/20 | 0.65 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.53 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | DTYMK | P23919 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15948322 | 1.00 | POLB (0.76) | POLBPOLA1POLD1TK1P2RY2 | |
| SCHEMBL23405862 | 1.00 | POLB (0.76) | POLBPOLA1POLD1TK1P2RY2 | |
| SCHEMBL17225234 | 1.00 | POLB (0.76) | POLBPOLA1POLD1TK1P2RY2 | |
| SCHEMBL24058347 | 1.00 | POLB (0.76) | POLBPOLA1POLD1TK1P2RY2 | |
| SCHEMBL17227489 | 0.95 | POLB (0.69) | POLBPOLA1POLD1TK1LMNA | |
| SCHEMBL22186553 | 0.91 | TK1 (0.77) | POLBPOLA1POLD1TK1LMNA | |
| SCHEMBL21579405 | 0.90 | POLB (0.71) | POLBPOLA1POLD1TK1DTYMK | |
| SCHEMBL17225231 | 0.90 | POLB (0.62) | POLBPOLA1POLD1TK1LMNA | |
| SCHEMBL7193310 | 0.90 | POLB (0.76) | POLBPOLA1POLD1TK1P2RY2 | |
| SCHEMBL27102380 | 0.90 | POLB (0.64) | POLBPOLA1POLD1TK1P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670539-B2 | Synthesis of cleavable fluorescent nucleotides as reversible terminators for DNA sequencing by synthesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-06-06 | — | — | US | disclosed |