Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16997309 | 0.85 | CYP2D6 (0.46) | TNKSTNKS2AVPR1ACCR5OPRM1 | |
| SCHEMBL12715975 | 0.80 | TNKS (0.44) | TNKSTNKS2AVPR1ACCR5OPRM1 | |
| SCHEMBL13640923 | 0.77 | TNKS (0.41) | TNKSTNKS2AVPR1ACCR5OPRM1 | |
| SCHEMBL1670650 | 0.77 | TNKS (0.46) | TNKSTNKS2AVPR1ACCR5OPRM1 | |
| SCHEMBL4268746 | 0.77 | SIGMAR1 (0.48) | TNKSTNKS2AVPR1ACCR5OPRM1 | |
| Hydrochloric Acid SCHEMBL25230408 | 0.76 | TNKS (0.45) | TNKSTNKS2AVPR1ACCR5OPRM1 | |
| Hydrochloric Acid SCHEMBL7006808 | 0.75 | TNKS (0.43) | TNKSTNKS2AVPR1ACCR5KCNH2 | |
| SCHEMBL1012828 | 0.75 | TNKS (0.44) | TNKSTNKS2AVPR1ACCR5OPRM1 | |
| SCHEMBL29479467 | 0.75 | TNKS (0.44) | TNKSTNKS2AVPR1ACCR5OPRM1 | |
| SCHEMBL4262381 | 0.74 | TNKS (0.40) | TNKSTNKS2AVPR1ACCR5OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10717737-B2 | Cyclopropylamines as LSD1 inhibitors | INCYTE CORPORATION (US) | 2020-07-21 | — | — | US | disclosed |
| US-20190211014-A1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | INCYTE CORPORATION | 2019-07-11 | — | — | US | disclosed |
| US-9670210-B2 | Cyclopropylamines as LSD1 inhibitors | INCYTE CORPORATION (US) | 2017-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10717737-B2 | Cyclopropylamines as LSD1 inhibitors | KDM1B, KDM1A, KDM2A | TNKS 345/4885TNKS2 325/4885AVPR1A 4523/4885 |
| US-20190211014-A1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | KDM1B, KDM1A, KDM2A | TNKS 345/4885TNKS2 325/4885AVPR1A 4523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.