Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.47 |
| ▸ | APP | P05067 | 3/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16069663 | 0.86 | KDM4E (0.46) | NPC1RAB9AALDH1A1CYP2C9KDM4E | |
| SCHEMBL18924201 | 0.82 | ALDH1A1 (0.47) | ESR1ESR2APPHSD17B3NPC1 | |
| SCHEMBL16069697 | 0.81 | MAPT (0.49) | NPC1RAB9AALDH1A1CYP2C9KDM4E | |
| SCHEMBL16069657 | 0.81 | PDE3B (0.41) | APPNPC1RAB9A | |
| SCHEMBL16069659 | 0.80 | ALDH1A1 (0.40) | NPC1RAB9AALDH1A1CYP2C9KDM4E | |
| SCHEMBL13212103 | 0.80 | APP (0.57) | ESR1ESR2APPHSD17B3NPC1 | |
| SCHEMBL16069665 | 0.77 | RAB9A (0.49) | NPC1RAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL18924241 | 0.76 | CA12 (0.50) | APPNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL18924100 | 0.76 | MAOB (0.52) | APPNPC1RAB9ACA12MAOB | |
| SCHEMBL29814693 | 0.76 | APP (0.59) | ESR1ESR2APPHSD17B3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670170-B2 | Resorufin derivatives for treatment of oxidative stress disorders | BIOELECTRON TECHNOLOGY CORPORATION (US) | 2017-06-06 | — | — | US | disclosed |