SCHEMBL18924281

SCHEMBL18924281

CCCc1cc(O)c(CCC)cc1C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 2/20 0.53
NPSR1 Q6W5P4 2/20 0.48
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
TDP1 Q9NUW8 5/20 0.41
RECQL P46063 3/20 0.41
THRB P10828 3/20 0.41
APEX1 P27695 2/20 0.41
RAD52 P43351 2/20 0.41
GAPDH P04406 1/20 0.41
BLM P54132 1/20 0.41
ALOX5 P09917 2/20 0.41
MAPT P10636 5/20 0.40
HTT P42858 4/20 0.40
KDM4E B2RXH2 3/20 0.40
MAPK1 P28482 3/20 0.40
ALDH1A1 P00352 3/20 0.40
POLB P06746 2/20 0.40
HKDC1 Q2TB90 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23387409 0.91 HMGCR (0.53) HMGCRNPSR1MEN1KMT2ATDP1
SCHEMBL5678026 0.88 HMGCR (0.45) HMGCRNPSR1MEN1KMT2ATDP1
SCHEMBL1760537 0.88 HMGCR (0.64) HMGCRMEN1KMT2ATDP1RECQL
SCHEMBL11705703 0.87 TYR (0.55) HMGCRNPSR1MEN1KMT2ATDP1
SCHEMBL14139877 0.86 NPSR1 (0.46) HMGCRNPSR1ALOX5MAPTHTT
SCHEMBL13842565 0.86 HMGCR (0.53) HMGCRNPSR1MEN1KMT2ATDP1
SCHEMBL7189577 0.86 HMGCR (0.53) HMGCRNPSR1MEN1KMT2ATDP1
SCHEMBL18179321 0.85 HMGCR (0.44) HMGCRNPSR1MEN1KMT2ATDP1
SCHEMBL23387419 0.84 HMGCR (0.45) HMGCRNPSR1MEN1KMT2ATDP1
SCHEMBL9141146 0.84 ALOX5 (0.58) MEN1KMT2ATDP1ALOX5MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3825145-A1 TIRE RUBBER COMPOSITION AND TIRE Sumitomo Rubber Industries, Ltd. (JP) 2021-05-26 EP disclosed
US-9670309-B2 Novolac-based epoxy compound, production method for same, composition and cured article comprising same, and use for same KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2017-06-06 US disclosed