Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12859785 | 1.00 | ADAM17 (0.44) | ADAM17KMT2AMEN1DPP4DPP8 | |
| SCHEMBL15679193 | 0.84 | ADAM17 (0.40) | ADAM17KMT2AMEN1MMP9ALDH1A1 | |
| SCHEMBL17992837 | 0.84 | ADAM17 (0.40) | ADAM17KMT2AMEN1MMP9ALDH1A1 | |
| SCHEMBL18272890 | 0.81 | ADAM17 (0.40) | ADAM17KMT2AMEN1MMP1MMP9 | |
| SCHEMBL26789813 | 0.81 | MMP1 (0.38) | ADAM17POLBMMP1MMP9MMP14 | |
| SCHEMBL30863359 | 0.81 | KMT2A (0.40) | ADAM17KMT2AMEN1DPP4DPP8 | |
| SCHEMBL27232661 | 0.81 | MMP1 (0.38) | KMT2AUSP2MMP1MMP9MMP14 | |
| SCHEMBL27210262 | 0.81 | MMP1 (0.38) | KMT2AUSP2MMP1MMP9MMP14 | |
| SCHEMBL19323901 | 0.81 | MMP1 (0.38) | KMT2AUSP2MMP1MMP9MMP14 | |
| SCHEMBL24337164 | 0.79 | MMP1 (0.38) | POLBMMP1MMP9MMP14FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670142-B2 | 1,3-diaminocyclopentane carboxamide derivatives | MERCK PATENT GMBH (DE) | 2017-06-06 | — | — | US | disclosed |