Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 11/20 | 0.67 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.48 |
| ▸ | GLS | O94925 | 5/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17546583 | 0.84 | KLKB1 (0.60) | KLKB1MLLT1GLSTPSAB1MIF | |
| SCHEMBL18924765 | 0.83 | KLKB1 (0.70) | KLKB1GLS | |
| SCHEMBL17540851 | 0.81 | KLKB1 (0.56) | KLKB1MLLT1GLSTPSAB1MIF | |
| SCHEMBL15873751 | 0.81 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL18646129 | 0.77 | ALDH1A1 (0.47) | KLKB1GLS | |
| SCHEMBL17503879 | 0.77 | KLKB1 (0.69) | KLKB1 | |
| SCHEMBL19322611 | 0.76 | KLKB1 (0.64) | KLKB1MLLT1TPSAB1 | |
| Hydrochloric Acid SCHEMBL15873849 | 0.76 | KLKB1 (0.68) | KLKB1 | |
| SCHEMBL14115874 | 0.74 | GLS (0.64) | GLSMIF | |
| SCHEMBL13787252 | 0.74 | GLS (0.64) | GLSMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670157-B2 | Benzylamine derivatives | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2017-06-06 | — | — | US | disclosed |