Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL638696 | 0.81 | — | — | |
| SCHEMBL1421996 | 0.81 | CHRM2 (0.39) | SMN1; SMN2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL978471 | 0.80 | — | — | |
| SCHEMBL612318 | 0.80 | — | — | |
| SCHEMBL1884135 | 0.77 | ALDH1A1 (0.34) | SMN1; SMN2KDM4E | |
| SCHEMBL1892476 | 0.77 | ALDH1A1 (0.34) | KDM4E | |
| SCHEMBL1891317 | 0.76 | HSD17B10 (0.31) | HSD17B10 | |
| SCHEMBL10650039 | 0.74 | SMN1; SMN2 (0.44) | LMNASMN1; SMN2CHRM2CHRM4CHRM1 | |
| SCHEMBL975944 | 0.74 | GAA (0.39) | LMNASMN1; SMN2TP53RAB9A | |
| SCHEMBL2957623 | 0.74 | GAA (0.39) | LMNASMN1; SMN2TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935686-B2 | Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use | XENOPORT, INC. (US) | 2011-05-03 | — | — | US | disclosed |
| WO-2006050472-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF 3-AMINOPROPYLPHOSPHONOUS AND -PHOSPHINIC ACIDS | XENOPORT, INC. (US) | 2006-05-11 | — | — | WO | disclosed |