Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1884135 | 0.90 | ALDH1A1 (0.34) | ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL1421996 | 0.83 | CHRM2 (0.39) | KDM4EL3MBTL1HPGD | |
| SCHEMBL1949591 | 0.79 | LMNA (0.41) | MAPT | |
| SCHEMBL1280223 | 0.77 | LMNA (0.40) | MAPT | |
| SCHEMBL1892479 | 0.77 | LMNA (0.36) | KDM4E | |
| SCHEMBL1727857 | 0.77 | GLA (0.32) | — | |
| SCHEMBL4440353 | 0.76 | TP53 (0.40) | ALDH1A1MAPT | |
| SCHEMBL5816927 | 0.76 | POLB (0.35) | — | |
| SCHEMBL7208632 | 0.75 | NPC1 (0.46) | ALDH1A1MAPT | |
| SCHEMBL244371 | 0.75 | LMNA (0.30) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935686-B2 | Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use | XENOPORT, INC. (US) | 2011-05-03 | — | — | US | disclosed |
| WO-2006050472-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF 3-AMINOPROPYLPHOSPHONOUS AND -PHOSPHINIC ACIDS | XENOPORT, INC. (US) | 2006-05-11 | — | — | WO | disclosed |