Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 4/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128660 | 0.85 | TSHR (0.48) | PRKCAMMP1MMP2MMP3MMP9 | |
| SCHEMBL21811595 | 0.84 | TSHR (0.43) | PRKCAMMP1MMP2MMP3MMP9 | |
| SCHEMBL2500451 | 0.83 | TSHR (0.46) | PRKCAMMP1MMP2MMP3MMP9 | |
| SCHEMBL27259225 | 0.83 | TSHR (0.46) | PRKCAMMP1MMP2MMP3MMP9 | |
| SCHEMBL26727662 | 0.81 | MAPT (0.52) | PRKCAMMP1MMP2MMP3MMP9 | |
| SCHEMBL14415222 | 0.81 | PRKCA (0.45) | PRKCAMMP1MMP2MMP3MMP9 | |
| SCHEMBL11004084 | 0.80 | PRKCA (0.41) | PRKCAMMP1MMP2MMP3MMP9 | |
| SCHEMBL16996650 | 0.79 | MMP1 (0.48) | PRKCAMMP1MMP2MMP3MMP9 | |
| SCHEMBL15148162 | 0.79 | PRKCA (0.52) | PRKCAMMP1MMP2MMP3MMP9 | |
| SCHEMBL2907463 | 0.79 | PRKCA (0.44) | PRKCAMMP1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670200-B2 | Quaternary ammonium salt prodrugs | ALKERMES PHARMA IRELAND LIMITED (IE) | 2017-06-06 | — | — | US | disclosed |