Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6896156 | 0.83 | LMNA (0.42) | LMNACA12CA1CA9CA2 | |
| SCHEMBL14870606 | 0.83 | LMNA (0.42) | LMNACA12CA1CA9CA2 | |
| SCHEMBL14870614 | 0.83 | LMNA (0.42) | LMNACA12CA1CA9CA2 | |
| SCHEMBL6895826 | 0.83 | LMNA (0.42) | LMNACA12CA1CA9CA2 | |
| SCHEMBL14870615 | 0.83 | LMNA (0.42) | LMNACA12CA1CA9CA2 | |
| SCHEMBL14870608 | 0.83 | LMNA (0.42) | LMNACA12CA1CA9CA2 | |
| SCHEMBL12507254 | 0.82 | LMNA (0.53) | LMNACA12CA1CA9CA2 | |
| SCHEMBL7522458 | 0.78 | FAAH (0.51) | LMNACA12CA1CA9CA2 | |
| SCHEMBL8989555 | 0.78 | FAAH (0.51) | LMNACA12CA1CA9CA2 | |
| SCHEMBL8968820 | 0.78 | FAAH (0.51) | LMNACA12CA1CA9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670200-B2 | Quaternary ammonium salt prodrugs | ALKERMES PHARMA IRELAND LIMITED (IE) | 2017-06-06 | — | — | US | disclosed |