Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | RARB | P10826 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL50604 | 1.00 | TSHR (0.54) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL3991691 | 0.93 | CES2 (0.53) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL3994964 | 0.93 | CES2 (0.53) | TSHRDAONAPRTCES2CES1 | |
| Terephthalic Acid SCHEMBL28928410 | 0.92 | RARB (0.55) | TSHRRARBTP53PLA2G4B | |
| Benzoic Acid SCHEMBL11830370 | 0.88 | TSHR (0.58) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL6573567 | 0.86 | TSHR (0.67) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL9157936 | 0.86 | TSHR (0.67) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28845500 | 0.86 | TSHR (0.67) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27413851 | 0.86 | TSHR (0.67) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL9594281 | 0.86 | TSHR (0.67) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118027886-A | Double-component organic silicon sealant for photovoltaic module and preparation method thereof | 杭州之江有机硅化工有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-111807723-A | Low-E hollow glass and preparation method thereof | 宜城佳海玻璃有限公司 | 2020-10-23 | — | — | CN | claimed |
| JP-4057858-A | — | — | None | — | — | JP | disclosed |
| CN-119177107-B | Glue for SPC board and preparation method thereof | 有行鲨鱼（上海）科技股份有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-119177107-A | Glue for SPC board and preparation method thereof | 有行鲨鱼（上海）科技股份有限公司 | 2024-12-24 | — | — | CN | disclosed |
| CN-118027886-A | Double-component organic silicon sealant for photovoltaic module and preparation method thereof | 杭州之江有机硅化工有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-116694288-B | Flame-retardant modified silane sealant and preparation method thereof | 湖南盛世胶业科技有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-116694288-A | Flame-retardant modified silane sealant and preparation method thereof | 湖南盛世胶业科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| US-20230140993-A1 | ORGANOPOLYSILOXANE AND CURABLE COMPOSITION CONTAINING SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-05-11 | — | — | US | disclosed |
| EP-4122939-A1 | ORGAOPOLYSILOXANE AND CURABLE COMPOSITION CONTAINING SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-01-25 | — | — | EP | disclosed |
| CN-113528079-B | Silicone sealant for PP (polypropylene) material and preparation method thereof | 杭州之江新材料有限公司 | 2022-11-18 | — | — | CN | disclosed |
| US-6312813-B1 | BLOCKED POLYISOCYANATE COMPOUND AND BENZOIC ACID AND/OR SALICYLIC ACID; EXCELLENT IN GLOSS AND LEVELLING PROPERTY | KANSAI PAINT CO., LTD. (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-1099542-A1 | Plastic-coated metal plate | KANSAI PAINT CO., LTD. (JP) | 2001-05-16 | — | — | EP | disclosed |
| EP-1035176-A1 | Cation-electrodepositable resin composition | KANSAI PAINT CO., LTD. (JP) | 2000-09-13 | — | — | EP | disclosed |
| US-6048926-A | Aqueous two component polyurethane coatings, preparation thereof and use thereof | HUELS AKTIENGESELLSCHAFT (DE) | 2000-04-11 | — | — | US | disclosed |
| EP-0839846-B1 | Aqueous two component polyurethane coating agent, process for its production and use | DEGUSSA (DE) | 1999-11-17 | — | — | EP | disclosed |
| EP-0839846-A1 | Aqueous two component polyurethane coating agent, process for its production and use | HÜLS AKTIENGESELLSCHAFT (DE) | 1998-05-06 | — | — | EP | disclosed |
| JP-H0457858-A | MANUFACTURE OF CATIONIC ELECTRODEPOSITION PAINT | KANSAI PAINT CO LTD | 1992-02-25 | — | — | JP | disclosed |
| US-4085077-A | HEAT DISCOLORATION RESISTANCE | M&T CHEMICALS INC. (US) | 1978-04-18 | — | — | US | disclosed |
| US-3980622-A | Polymerizable emulsifying agent and application thereof | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1976-09-14 | — | — | US | disclosed |