Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | RARB | P10826 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL1892499 | 1.00 | TSHR (0.54) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL3991691 | 0.93 | CES2 (0.53) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL3994964 | 0.93 | CES2 (0.53) | TSHRDAONAPRTCES2CES1 | |
| Terephthalic Acid SCHEMBL28928410 | 0.92 | RARB (0.55) | TSHRRARBTP53PLA2G4B | |
| Benzoic Acid SCHEMBL11830370 | 0.88 | TSHR (0.58) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL6573567 | 0.86 | TSHR (0.67) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL9157936 | 0.86 | TSHR (0.67) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28845500 | 0.86 | TSHR (0.67) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27413851 | 0.86 | TSHR (0.67) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL9594281 | 0.86 | TSHR (0.67) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119055555-A | PEG-PLA copolymer composite solution, preparation method and application thereof | 渼颜空间(河北)生物科技有限公司 | 2024-12-03 | — | — | CN | claimed |
| CN-118976147-A | Injectable filling microsphere, preparation containing injectable filling microsphere, preparation method and application of injectable filling microsphere | 北京渼颜空间生物医药有限公司 | 2024-11-19 | — | — | CN | claimed |
| CN-118976148-A | Injectable filling microsphere, injectable filling material containing injectable filling microsphere, and preparation and application of injectable filling microsphere | 北京渼颜空间生物医药有限公司 | 2024-11-19 | — | — | CN | claimed |
| CN-118834377-A | PLA-PEG-PLA block copolymer, injectable filling microsphere, and preparation method and application thereof | 北京渼颜空间生物医药有限公司 | 2024-10-25 | — | — | CN | claimed |
| CN-113242897-B | Adhesive agent | 美国陶氏有机硅公司 | 2024-06-14 | — | — | CN | claimed |
| CN-116285596-B | Preparation method and application of anti-shrinkage cathode electrophoretic coating | 广东科德环保科技股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| US-11926708-B1 | Fluorosilicone compositions and methods related thereto | NUSIL TECHNOLOGY LLC (US) | 2024-03-12 | — | — | US | claimed |
| EP-3673027-B1 | DUAL CURE ADHESIVE COMPOSITION AND METHODS FOR ITS PREPARATION AND USE | DOW SILICONES CORP (US) | 2023-11-01 | — | — | EP | claimed |
| CN-116376498-A | Adhesive agent | 美国陶氏有机硅公司 | 2023-07-04 | — | — | CN | claimed |
| CN-116355238-A | Copolymer hydrogel of polycaprolactone polyethylene glycol and derivatives thereof, and preparation method and application thereof | 北京渼颜空间生物医药有限公司 | 2023-06-30 | — | — | CN | claimed |
| EP-0688827-A2 | Method of preparing in situ reinforced silicone elastomer | DOW CORNING CORPORATION (US) | 1995-12-27 | — | — | EP | claimed |
| US-5468829-A | In-situ reinforced silicone elastomer using resin precursor | DOW CORNING CORPORATION (US) | 1995-11-21 | — | — | US | claimed |
| US-5395908-A | Method of preparing in situ reinforced silicone elastomer | DOW CORNING CORPORATION (US) | 1995-03-07 | — | — | US | claimed |
| EP-0509437-B1 | Electrocoating composition | KANSAI PAINT CO LTD (JP) | 1995-01-25 | — | — | EP | claimed |
| US-5330839-A | Electrocoating composition containing blocked isocyanate, dialkyltin aromatic carboxylate and a bismuth or zirconium compound | KANSAI PAINT CO., LTD. (JP) | 1994-07-19 | — | — | US | claimed |
| US-5260348-A | Chainstopped polysiloxane, a crosslinking agent and an onium catalyst | GENERAL ELECTRIC COMPANY (US) | 1993-11-09 | — | — | US | claimed |
| US-5213899-A | ROOM TEMPERATURE VULCANIZABLE SILICONE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1993-05-25 | — | — | US | claimed |
| EP-0509437-A1 | Electrocoating composition | KANSAI PAINT CO., LTD. (JP) | 1992-10-21 | — | — | EP | claimed |
| US-4973737-A | ORGANOTIN OR ORGANOTITANATE CATALYST, BY-PRODUCT INHIBITION | KABUSHIKI KAISHA VENO SEIYAKU OYO KENKYUO (JP) | 1990-11-27 | — | — | US | claimed |
| US-4461867-A | CONTAINING A DIORGANOCYCLOPOLYSILOXANE COMPOUND | GENERAL ELECTRIC COMPANY (US) | 1984-07-24 | — | — | US | claimed |