SCHEMBL1892592

SCHEMBL1892592

CC1=CCC(F)(C(=O)O)C=C1

nearest known ligand 0.40

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28980668 0.77 HSD11B1 (0.40) HSD11B1
SCHEMBL28913672 0.77
SCHEMBL20420817 0.74 HSD11B1 (0.41) HSD11B1
SCHEMBL2470442 0.74 HSD11B1 (0.41) HSD11B1
SCHEMBL11543971 0.73 HSD11B1 (0.40) HSD11B1
SCHEMBL15387141 0.73
SCHEMBL31559989 0.69 APP (0.34)
SCHEMBL29086601 0.68 HSD11B1 (0.39) HSD11B1
SCHEMBL28844089 0.68 HSD11B1 (0.39) HSD11B1
SCHEMBL25336093 0.67 HSD11B1 (0.38) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1797186-B1 EXPRESSION SYSTEM, COMPONENTS THEREOF AND METHODS OF USE NAT RES COUNCIL CANADA (CA) 2016-05-25 EP claimed
US-8728759-B2 Reverse cumate repressor mutant NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2014-05-20 US claimed
US-8252556-B2 Reverse cumate repressor mutant NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2012-08-28 US claimed
US-20110171686-A1 REVERSE CUMATE REPRESSOR MUTANT NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2011-07-14 US claimed
US-20090176275-A1 EXPRESSION SYSTEM, COMPONENTS THEREOF AND METHODS OF USE NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2009-07-09 US claimed
US-20080311618-A1 Expression System, Components Thereof and Methods of Use NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2008-12-18 US claimed
EP-1797186-A4 EXPRESSION SYSTEM, COMPONENTS THEREOF AND METHODS OF USE CA NAT RESEARCH COUNCIL (CA) 2008-11-12 EP claimed
EP-1797186-A1 EXPRESSION SYSTEM, COMPONENTS THEREOF AND METHODS OF USE NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2007-06-20 EP claimed
WO-2006037215-A1 EXPRESSION SYSTEM, COMPONENTS THEREOF AND METHODS OF USE NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2006-04-13 WO claimed
US-20040205834-A1 System for inducible expression in eukaryotic cells NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2004-10-14 US claimed
US-12351813-B2 Tetracycline-inducible expression system DNA TWOPOINTO INC. (US) 2025-07-08 US disclosed
WO-2025072098-A1 INDUCIBLE EXPRESSION SYSTEMS DNA TWOPOINTO INC. (US) 2025-04-03 WO disclosed
US-20240425875-A1 EXPRESSION SYSTEM FOR CONSTITUTIVE OR CUMATE-INDUCIBLE EXPRESSION IN CHO CELLS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2024-12-26 US disclosed
EP-4402273-A1 EXPRESSION SYSTEM FOR CONSTITUTIVE OR CUMATE-INDUCIBLE EXPRESSION IN CHO CELLS National Research Council of Canada (CA) 2024-07-24 EP disclosed
US-20230323396-A1 TETRACYCLINE-INDUCIBLE EXPRESSION SYSTEM DNA TWOPOINTO INC. (US) 2023-10-12 US disclosed
US-20080311618-A1 Expression System, Components Thereof and Methods of Use NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2008-12-18 US disclosed
EP-1797186-A4 EXPRESSION SYSTEM, COMPONENTS THEREOF AND METHODS OF USE CA NAT RESEARCH COUNCIL (CA) 2008-11-12 EP disclosed
EP-1797186-A1 EXPRESSION SYSTEM, COMPONENTS THEREOF AND METHODS OF USE NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2007-06-20 EP disclosed
WO-2006037215-A1 EXPRESSION SYSTEM, COMPONENTS THEREOF AND METHODS OF USE NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2006-04-13 WO disclosed
US-20040205834-A1 System for inducible expression in eukaryotic cells NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2004-10-14 US disclosed