Sugi Predict

Sugi Predict / Compounds / SCHEMBL18926280

SCHEMBL18926280

SCHEMBL18926280

Cc1ccc(-c2cc(-c3ccc(C)cc3)nc(-n3c4ccccc4c4c5ccc6c7ccccc7n(-c7ccccc7)c6c5ccc43)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.39
▸ RXFP1 Q9HBX9 2/20 0.39
▸ KDM4E B2RXH2 5/20 0.39
▸ MAPT P10636 3/20 0.39
▸ L3MBTL1 Q9Y468 3/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ HPGD P15428 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ NPC1 O15118 1/20 0.38
▸ STAT1 P42224 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ FLT3 P36888 1/20 0.37
▸ GAA P10253 2/20 0.36
▸ LMNA P02545 1/20 0.36
▸ AGTR1 P30556 1/20 0.36
▸ ATM Q13315 1/20 0.36
▸ MAPK1 P28482 2/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22995668 0.93 ALDH1A1 (0.40) ALDH1A1RXFP1KDM4EMAPTL3MBTL1
SCHEMBL18926279 0.92 L3MBTL1 (0.39) ALDH1A1RXFP1KDM4EMAPTL3MBTL1
SCHEMBL18926283 0.92 L3MBTL1 (0.41) ALDH1A1RXFP1KDM4EMAPTL3MBTL1
SCHEMBL16353109 0.89 ALDH1A1 (0.43) ALDH1A1RXFP1KDM4EMAPTL3MBTL1
SCHEMBL15625697 0.86 L3MBTL1 (0.40) ALDH1A1RXFP1KDM4EMAPTL3MBTL1
SCHEMBL17248251 0.86 L3MBTL1 (0.40) ALDH1A1RXFP1KDM4EMAPTL3MBTL1
SCHEMBL12131958 0.86 L3MBTL1 (0.41) ALDH1A1RXFP1KDM4EMAPTL3MBTL1
SCHEMBL15073463 0.85 L3MBTL1 (0.45) ALDH1A1RXFP1KDM4EMAPTL3MBTL1
SCHEMBL17248163 0.83 ALDH1A1 (0.41) ALDH1A1RXFP1KDM4EMAPTL3MBTL1
SCHEMBL17248253 0.83 L3MBTL1 (0.41) ALDH1A1KDM4EMAPTL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9806271-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-10-31 — — US disclosed
US-9806271-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-10-31 — — US disclosed
US-20170162797-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-06-08 — — US disclosed
US-20170162797-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-06-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170162797-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME L1CAM, CHRM1, OR10J3 ALDH1A1 212/4885RXFP1 780/4885KDM4E 1864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.