Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2373646 | 0.77 | PDPK1 (0.63) | PDPK1CCNA2CDK2CCNA1TSHR | |
| SCHEMBL8988198 | 0.73 | PDPK1 (0.59) | PDPK1CCNA2CDK2CCNA1TSHR | |
| SCHEMBL13162008 | 0.67 | — | — | |
| SCHEMBL16212301 | 0.67 | PDE10A (0.47) | — | |
| SCHEMBL8080735 | 0.65 | — | — | |
| SCHEMBL2155849 | 0.65 | — | — | |
| SCHEMBL7457466 | 0.65 | HPGD (0.58) | HTTPOLBTSHRMAPTKDM4E | |
| SCHEMBL15651802 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL18209988 | 0.64 | PDPK1 (0.96) | PDPK1CCNA2CDK2CCNA1TSHR | |
| SCHEMBL6474889 | 0.63 | TSHR (0.59) | HTTPOLBTSHRMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3176168-A1 | PYRAZOLE DERIVATIVE MANUFACTURING METHOD | Mochida Pharmaceutical Co., Ltd. (JP) | 2017-06-07 | — | — | EP | disclosed |