Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18928458 | 0.87 | NR1I2 (0.34) | NR1I2 | |
| SCHEMBL18928394 | 0.87 | NR1I2 (0.33) | NR1I2 | |
| SCHEMBL18928374 | 0.84 | NR1I2 (0.34) | NR1I2 | |
| SCHEMBL18929004 | 0.84 | NR1I2 (0.45) | NR1I2 | |
| SCHEMBL18944148 | 0.82 | NR1I2 (0.38) | NR1I2 | |
| SCHEMBL18928179 | 0.82 | NR1I2 (0.36) | NR1I2 | |
| SCHEMBL18928384 | 0.82 | PDE4A (0.34) | NR1I2 | |
| SCHEMBL18928365 | 0.82 | NR1I2 (0.36) | NR1I2 | |
| SCHEMBL18928449 | 0.81 | NR1I2 (0.33) | NR1I2 | |
| SCHEMBL18928562 | 0.81 | NR1I2 (0.36) | NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093938-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES | VIIV HEALTHCARE UK LIMITED (GB) | 2017-06-08 | — | — | WO | disclosed |