Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18928374 | 0.93 | NR1I2 (0.34) | NR1I2PDE4A | |
| SCHEMBL18928319 | 0.91 | NR1I2 (0.34) | NR1I2PDE4A | |
| SCHEMBL18928384 | 0.91 | PDE4A (0.34) | NR1I2PDE4A | |
| SCHEMBL18928142 | 0.87 | HTR4 (0.33) | NR1I2PDE4A | |
| SCHEMBL18928344 | 0.86 | NR1I2 (0.35) | NR1I2PDE4A | |
| SCHEMBL18928448 | 0.84 | NR1I2 (0.42) | NR1I2PDE4A | |
| SCHEMBL18928496 | 0.84 | NR1I2 (0.34) | NR1I2PDE4A | |
| SCHEMBL18928421 | 0.84 | HTR4 (0.35) | PDE4A | |
| SCHEMBL18928355 | 0.83 | NR1I2 (0.36) | NR1I2PDE4A | |
| SCHEMBL18928331 | 0.83 | NR1I2 (0.36) | NR1I2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093938-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES | VIIV HEALTHCARE UK LIMITED (GB) | 2017-06-08 | — | — | WO | disclosed |