Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | EGFR | P00533 | 3/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19831621 | 0.76 | CES2 (0.36) | SMN1; SMN2 | |
| SCHEMBL19831560 | 0.73 | MAOB (0.33) | ATMPOLBMAOAMAOBRECQL | |
| SCHEMBL24097054 | 0.72 | ATM (0.44) | ATMEGFRRECQL | |
| SCHEMBL20999159 | 0.72 | AKT1 (0.36) | ATMPOLBEGFRRECQLSMN1; SMN2 | |
| SCHEMBL15216219 | 0.72 | ATM (0.35) | ATMPOLBEGFRRECQLSMN1; SMN2 | |
| SCHEMBL13716855 | 0.70 | F2 (0.36) | ATMEGFRRECQL | |
| SCHEMBL20470769 | 0.70 | AKT1 (0.46) | ATMSMN1; SMN2 | |
| SCHEMBL18868783 | 0.70 | AKT1 (0.46) | ATMSMN1; SMN2 | |
| SCHEMBL18868913 | 0.68 | CES2 (0.37) | ATMPOLBSMN1; SMN2 | |
| SCHEMBL16603265 | 0.67 | POLB (0.33) | POLBRECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922841-B1 | ALKYL-AMIDE-SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES | BRISTOL MYERS SQUIBB CO (US) | 2017-06-07 | — | — | EP | disclosed |