Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20077791 | 0.85 | DEGS1 (0.41) | CES2CES1ALDH1A1LMNAMEN1 | |
| SCHEMBL26306846 | 0.80 | ALDH1A1 (0.46) | CES2CES1ALDH1A1LMNAMEN1 | |
| SCHEMBL18400550 | 0.80 | GAA (0.39) | CES2CES1ALDH1A1LMNAMEN1 | |
| SCHEMBL20908860 | 0.76 | MEN1 (0.32) | LMNAMEN1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL19831082 | 0.76 | TDP1 (0.35) | ALDH1A1LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL20470769 | 0.76 | AKT1 (0.46) | CES2CES1ALDH1A1LMNAMEN1 | |
| SCHEMBL13716855 | 0.76 | F2 (0.36) | CES2CES1ALDH1A1LMNAMEN1 | |
| SCHEMBL18868783 | 0.76 | AKT1 (0.46) | CES2CES1ALDH1A1LMNAMEN1 | |
| SCHEMBL21574102 | 0.75 | ALDH1A1 (0.30) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL22649497 | 0.75 | CES2 (0.49) | CES2CES1ALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230403927-A1 | AROMATIC COMPOUNDS | UDC IRELAND LTD (IE) | 2023-12-14 | — | — | US | disclosed |
| US-11800787-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2023-10-24 | — | — | US | disclosed |
| US-20170141329-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230403927-A1 | AROMATIC COMPOUNDS | TYR, CTCF, MITF | CES2 2732/4885CES1 4860/4885ALDH1A1 1461/4885 |
| US-20170141329-A1 | METAL COMPLEXES | AP1M1, SOD1, AP3M1 | CES2 3138/4885CES1 4802/4885ALDH1A1 3771/4885 |
| US-11800787-B2 | Metal complexes | AP1M1, SOD1, AP3M1 | CES2 3138/4885CES1 4802/4885ALDH1A1 3771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.