Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16250326 | 0.89 | NOD1 (0.39) | NOD1KMT2APOLBL3MBTL1 | |
| SCHEMBL16250328 | 0.89 | NOD1 (0.39) | NOD1KMT2APOLBL3MBTL1 | |
| SCHEMBL19477961 | 0.87 | ALDH1A1 (0.36) | — | |
| SCHEMBL22301081 | 0.87 | ALDH1A1 (0.36) | — | |
| SCHEMBL22372637 | 0.83 | NOD1 (0.34) | NOD1KMT2APOLB | |
| SCHEMBL17448284 | 0.83 | NOD1 (0.36) | NOD1KMT2APOLBL3MBTL1 | |
| SCHEMBL26922716 | 0.83 | NOD1 (0.36) | NOD1KMT2APOLBL3MBTL1 | |
| SCHEMBL24383365 | 0.81 | NOD1 (0.35) | NOD1KMT2APOLBL3MBTL1 | |
| SCHEMBL20756564 | 0.81 | NOD1 (0.36) | NOD1KMT2APOLBL3MBTL1 | |
| SCHEMBL23446568 | 0.79 | ALDH1A1 (0.42) | NOD1KMT2APOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170159055-A1 | COMPOSITIONS AND METHODS FOR MODULATING COMPLEMENT FACTOR B EXPRESSION | IONIS PHARMACEUTICALS, INC. (US) | 2017-06-08 | — | — | US | disclosed |