Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 17/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1896357 | 0.92 | TLR7 (0.49) | TLR7TLR8NUDT1BRD4PDE10A | |
| SCHEMBL1894838 | 0.91 | TLR7 (0.54) | TLR7TLR8 | |
| SCHEMBL1896178 | 0.91 | TLR7 (0.57) | TLR7TLR8NUDT1 | |
| SCHEMBL1896264 | 0.90 | TLR7 (0.45) | TLR7TLR8NUDT1BRD4LRRK2 | |
| SCHEMBL1897538 | 0.83 | TLR7 (0.65) | TLR7TLR8NUDT1 | |
| SCHEMBL1896707 | 0.82 | TLR7 (0.46) | TLR7TLR8PDE10A | |
| SCHEMBL5354699 | 0.82 | TLR7 (0.47) | TLR7TLR8PDE10A | |
| SCHEMBL1894998 | 0.82 | TLR7 (0.39) | TLR7TLR8NUDT1 | |
| SCHEMBL1894186 | 0.81 | TLR7 (0.54) | TLR7TLR8NUDT1 | |
| SCHEMBL5349584 | 0.78 | TLR7 (0.52) | TLR7TLR8PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939526-B2 | Sulfone substituted imidazo ring ethers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-05-10 | — | — | US | disclosed |
| US-20070155767-A1 | Sulfone substituted imidazo ring ethers | 3M INNOVATIVE PROPERTIES COMPANY | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155767-A1 | Sulfone substituted imidazo ring ethers | IL2, IL4, IFNG | TLR7 82/4885TLR8 145/4885NUDT1 2054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.