SCHEMBL572196

SCHEMBL572196

[CH2]C(Cl)(Cl)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1012277 0.80
SCHEMBL20803 0.78
SCHEMBL18931 0.78
SCHEMBL28647441 0.73
SCHEMBL17456614 0.72
SCHEMBL8378533 0.70 LMNA (0.30)
SCHEMBL8660208 0.70
SCHEMBL589093 0.70
SCHEMBL21268077 0.70
SCHEMBL588690 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1129083-A1 ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES NIHON BAYER AGROCHEM K.K. (JP) 2001-09-05 EP claimed
WO-2000029398-A1 ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES NIHON BAYER AGROCHEM K.K. (JP) 2000-05-25 WO claimed
US-RE36617-E Anastrozole and salts as anticancer agent ZENECA LIMITED (GB) 2000-03-14 US claimed
EP-0296749-B1 (Substituted aralkyl) heterocyclic compounds ZENECA LTD (GB) 1994-10-26 EP claimed
US-4935437-A (Substituted aralkyl) heterocyclic compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-06-19 US claimed
US-4916148-A AROMATASE INHIBITORS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-04-10 US claimed
EP-0316097-A1 Naphtho(2,1-b)furan derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-05-17 EP claimed
EP-0296749-A1 (Substituted aralkyl) heterocyclic compounds ZENECA LIMITED (GB) 1988-12-28 EP claimed
CN-105573055-B Colored curable resin composition 住友化学株式会社 2020-11-17 CN disclosed
CN-107111230-B Colored curable resin composition 东友精细化工有限公司 2020-09-08 CN disclosed
CN-109071386-A The manufacturing method of the chloro- 3,3,3- trifluoro propene of 1,2- bis- 中央硝子株式会社 2018-12-21 CN disclosed
EP-2600825-B1 Method for curling hair AC PATENT HOLDING INC (US) 2018-12-12 EP disclosed
CN-105573055-A COLORED CURABLE RESIN COMPOSITION SUMITOMO CHEMICAL CO 2016-05-11 CN disclosed
EP-2162429-B1 HALOGEN-CONTAINING ORGANOSULFUR COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2016-04-13 EP disclosed
US-4935437-A (Substituted aralkyl) heterocyclic compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-06-19 US disclosed
US-4916148-A AROMATASE INHIBITORS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-04-10 US disclosed
EP-0316097-A1 Naphtho(2,1-b)furan derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-05-17 EP disclosed
EP-0296749-A1 (Substituted aralkyl) heterocyclic compounds ZENECA LIMITED (GB) 1988-12-28 EP disclosed
EP-0245209-A1 Milbemycin derivatives, their preparation and their use as pesticides CIBA-GEIGY AG (CH) 1987-11-11 EP disclosed
EP-0195743-A2 Enol ethers, process for their preparation, alpha-pyrones, process for their preparation and use of the alpha-pyrones CIBA-GEIGY AG (CH) 1986-09-24 EP disclosed