Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 11/20 | 0.69 |
| ▸ | TSHR | P16473 | 11/20 | 0.69 |
| ▸ | HPGD | P15428 | 10/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | GLA | P06280 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | CASP1 | P29466 | 3/20 | 0.56 |
| ▸ | CASP7 | P55210 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4759826 | 0.85 | ALDH1A1 (0.69) | ALDH1A1KDM4EHSD17B10TSHRHPGD | |
| SCHEMBL8244817 | 0.84 | ALDH1A1 (0.69) | ALDH1A1KDM4EHSD17B10TSHRHPGD | |
| SCHEMBL4708938 | 0.84 | ALDH1A1 (0.69) | ALDH1A1KDM4EHSD17B10TSHRHPGD | |
| SCHEMBL4713044 | 0.84 | ALDH1A1 (0.95) | ALDH1A1KDM4EHSD17B10TSHRHPGD | |
| SCHEMBL4759842 | 0.84 | ALDH1A1 (0.69) | ALDH1A1KDM4EHSD17B10TSHRHPGD | |
| SCHEMBL4710590 | 0.83 | ALDH1A1 (0.74) | ALDH1A1KDM4EHSD17B10TSHRHPGD | |
| SCHEMBL4790925 | 0.83 | ALDH1A1 (0.66) | ALDH1A1KDM4EHSD17B10TSHRHPGD | |
| SCHEMBL8805983 | 0.82 | ALDH1A1 (0.65) | ALDH1A1KDM4EHSD17B10TSHRHPGD | |
| SCHEMBL4714112 | 0.82 | ALDH1A1 (0.66) | ALDH1A1KDM4EHSD17B10TSHRHPGD | |
| SCHEMBL4710374 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KDM4EHSD17B10TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10179929-B2 | Water-soluble activatable molecular probes, intermediates for the synthesis thereof and associated detection methods | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2019-01-15 | — | — | US | disclosed |
| US-20170159100-A1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-06-08 | — | — | US | disclosed |
| US-20170159100-A1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10179929-B2 | Water-soluble activatable molecular probes, intermediates for the synthesis thereof and associated detection methods | SI, GUSB, ABCG2 | ALDH1A1 426/4885KDM4E 4802/4885HSD17B10 1954/4885 |
| US-20170159100-A1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | SI, GUSB, ABCG2 | ALDH1A1 426/4885KDM4E 4802/4885HSD17B10 1954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.