SCHEMBL189322

SCHEMBL189322

Oc1ccc(F)c(Br)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29427145 1.00
SCHEMBL31348999 0.81 ESR2 (0.50)
SCHEMBL177370 0.79
SCHEMBL29692338 0.79
SCHEMBL3395849 0.77 NPC1 (0.65)
SCHEMBL13263896 0.75 CES2 (0.53)
SCHEMBL2277159 0.75 MAPT (0.56)
SCHEMBL15552163 0.75 ESR1 (0.48)
SCHEMBL31521715 0.75 ESR1 (0.41)
SCHEMBL1047274 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 793 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116478199-A Bimetallic catalyst and preparation method thereof, and preparation method of high molecular weight olefin polymer 万华化学集团股份有限公司 2023-07-25 CN claimed
CN-100564339-C 2, the preparation method of 3-two fluoro-5-bromophenols SHANGHAI KANGPENG CHEMICAL CO (CN) 2009-12-02 CN claimed
CN-101037380-A Preparation method of 2,3-Difluoro-5-Bromophenol SHANGHAI KANGPENG CHEMICAL CO (CN) 2007-09-19 CN claimed
CN-1301946-C Preparation method of 2.3-difluoro-5-bromophenol FUXIN JINHONGTAI CHEMICAL CO L (CN) 2007-02-28 CN claimed
CN-1789224-A Preparation method of 2.3-difluoro-5-bromophenol FUXIN JINHONGTAI CHEMICAL CO L (CN) 2006-06-21 CN claimed
EP-4747247-A1 NOVEL FATTY ACID AMIDE HYDROLASE MODULATORS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF Apogee Pharmaceuticals, Inc. (CA) 2026-05-27 EP disclosed
US-12630528-B2 Amino aryl derivative useful as diacylglycerol acyltransferase 2 inhibitor and use thereof LG CHEM, LTD. (KR) 2026-05-19 US disclosed
US-12624051-B2 Macrocyclic compounds, compositions, and methods of using thereof GENZYME CORPORATION (US) 2026-05-12 US disclosed
US-12577242-B2 Pyrrolopyridine and imidazopyridine antiviral compounds KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2026-03-17 US disclosed
US-12552770-B2 Compounds for treating respiratory disease TMEM16A LIMITED (GB) 2026-02-17 US disclosed
US-20260034127-A1 TREATMENT OF GVHD KADMON CORP LLC (FR) 2026-02-05 US disclosed
US-20260035361-A1 COMPOUNDS FOR MODULATING HUR (ELAVL1) SHANGHAI DEGRON BIOMEDICAL TECH CO LTD (CN) 2026-02-05 US disclosed
WO-2000026182-A1 2-PHENOXYPHENYLACETIC ACID DERIVATIVES, METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION THEREOF, THEIR USE, AND AGENTS CONTAINING THE SAME FOR COMBATING FUNGICIDAL PESTS BASF AKTIENGESELLSCHAFT (DE) 2000-05-11 WO disclosed
US-5112523-A High clearing point for liquid crystal displays CHISSO CORPORATION (JP) 1992-05-12 US disclosed
CN-1015545-B preparation method of glycolic acid derivative for treating diabetic complications PFIZER (US) 1992-02-19 CN disclosed
EP-0230379-B1 CHROMAN- AND THIOCHROMAN-4-ACETIC ACIDS USEFUL IN THE TREATMENT OF DIABETIC COMPLICATIONS PFIZER INC. (US) 1991-04-03 EP disclosed
US-4874546-A LIQUID CRYSTALS CHISSO CORPORATION (JP) 1989-10-17 US disclosed
CN-87100191-A The hydroxy acid derivative of treatment diabetic complication 1987-09-09 CN disclosed
WO-1987004344-A1 HYDROXYACETIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETIC COMPLICATIONS PFIZER INC. (US) 1987-07-30 WO disclosed
EP-0230379-A2 Chroman- and thiochroman-4-acetic acids useful in the treatment of diabetic complications PFIZER INC. (US) 1987-07-29 EP disclosed