⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27475615 | 1.00 | — | — | |
| SCHEMBL27413768 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL27834237 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL27511055 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL27852327 | 0.98 | — | — | |
| Methylamine SCHEMBL27752718 | 0.78 | SLC1A3 (0.35) | — | |
| SCHEMBL12897756 | 0.78 | CA2 (0.50) | — | |
| SCHEMBL8284662 | 0.77 | — | — | |
| SCHEMBL8018182 | 0.77 | — | — | |
| SCHEMBL8012127 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10183950-B2 | Thienopyrimidine inhibitors of atypical protein kinase C | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2019-01-22 | — | — | US | disclosed |
| US-20170158706-A1 | THIENOPYRIMIDINE INHIBITORS OF ATYPICAL PROTEIN KINASE C | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2017-06-08 | — | — | US | disclosed |
| CN-102282147-B | Bicyclic pyrazolo-heterocycles | CARA THERAPEUTICS, INC. (US) | 2015-09-30 | — | — | CN | disclosed |
| CN-103298788-A | Pyridine derivative and medicinal agent | NIPPON SHINYAKU CO LTD | 2013-09-11 | — | — | CN | disclosed |
| CN-102459306-A | Novel amide derivatives of steroidal [3,2-C ] pyrazole compounds having glucocorticoid activity | ASTRAZENECA AB | 2012-05-16 | — | — | CN | disclosed |
| CN-102282147-A | Bicyclic pyrazolo-heterocycles | — | 2011-12-14 | — | — | CN | disclosed |
| CN-1297436-A | Substd. pyrrolidine hydroxamate metalloprotease inhibitors | PROCTER & GAMBLE (US) | 2001-05-30 | — | — | CN | disclosed |