Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 5/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.38 |
| ▸ | USP8 | P40818 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21020660 | 0.86 | ALDH1A1 (0.44) | ALDH1A1CYP2A6CYP11B1CYP11B2AR | |
| SCHEMBL17129796 | 0.85 | ALDH1A1 (0.56) | ALDH1A1CYP2A6CYP11B1CYP11B2AR | |
| SCHEMBL10110951 | 0.84 | ALDH1A1 (0.56) | ALDH1A1CYP2A6CYP11B1CYP11B2EGLN2 | |
| SCHEMBL18934546 | 0.82 | AR (0.46) | ALDH1A1CYP2A6CYP11B1CYP11B2AR | |
| SCHEMBL10074338 | 0.80 | ADORA2A (0.44) | ALDH1A1CYP2A6CYP11B1CYP11B2AR | |
| SCHEMBL197716 | 0.79 | ALDH1A1 (0.52) | ALDH1A1CYP2A6CASP3TDP1 | |
| SCHEMBL17589591 | 0.77 | ALDH1A1 (0.47) | ALDH1A1CYP2A6ARCASP3USP8 | |
| SCHEMBL28626580 | 0.77 | ALDH1A1 (0.42) | ALDH1A1CYP2A6CYP11B1CYP11B2AR | |
| SCHEMBL29788076 | 0.76 | PTGDR2 (0.49) | ALDH1A1CYP11B1CYP11B2ARPTGDR2 | |
| SCHEMBL15856481 | 0.76 | PTGDR2 (0.49) | ALDH1A1CYP11B1CYP11B2ARPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3109231-B1 | CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG ELECTRONICS CO LTD (KR) | 2019-10-16 | — | — | EP | disclosed |
| WO-2017093958-A1 | BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES | IDEMITSU KOSAN CO., LTD. (JP) | 2017-06-08 | — | — | WO | disclosed |