Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 2/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KHK | P50053 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13656745 | 0.86 | ALDH1A1 (0.39) | CYP1A2KMT2AALDH1A1CTSCKCNH2 | |
| SCHEMBL23197951 | 0.84 | ALDH1A1 (0.38) | CYP1A2KMT2AALDH1A1CTSCKCNH2 | |
| SCHEMBL22519410 | 0.80 | CYP1A2 (0.37) | CYP1A2KMT2AKDM4ECHRM5CHRM3 | |
| SCHEMBL23866631 | 0.80 | CYP1A2 (0.37) | CYP1A2KMT2AKDM4ECHRM5CHRM3 | |
| SCHEMBL25221272 | 0.78 | CYP1A2 (0.49) | CYP1A2KMT2AKDM4ECHRM5CHRM3 | |
| SCHEMBL18934852 | 0.78 | KDM4E (0.48) | CYP1A2KMT2AKDM4EGHSRDPP9 | |
| Hydrochloric Acid SCHEMBL25218542 | 0.77 | CYP1A2 (0.47) | CYP1A2KMT2AKDM4ECHRM5CHRM3 | |
| SCHEMBL6008945 | 0.76 | KMT2A (0.56) | CYP1A2KMT2AKDM4ECHRM5CHRM3 | |
| SCHEMBL17997419 | 0.76 | CYP1A2 (0.46) | CYP1A2KMT2AKDM4ECHRM5CHRM3 | |
| SCHEMBL18390291 | 0.74 | CYP1A2 (0.45) | CYP1A2KMT2AKDM4ECHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170158702-A1 | MULTIVALENT RAS BINDING COMPOUNDS | KYRAS THERAPEUTICS, INC. | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158702-A1 | MULTIVALENT RAS BINDING COMPOUNDS | KRAS, HRAS, NRAS | CYP1A2 4882/4885KMT2A 3584/4885KDM4E 3955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.