Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 6/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18934522 | 0.91 | LCK (0.44) | MAPK10MAPK8MAPK14KMT2ALCK | |
| SCHEMBL18934627 | 0.91 | MAPK8 (0.41) | MAPK10MAPK8MAPK14KMT2ALCK | |
| SCHEMBL18934624 | 0.88 | MAPK8 (0.41) | MAPK10MAPK8MAPK14KMT2ALCK | |
| SCHEMBL18934879 | 0.79 | KMT2A (0.47) | KMT2ALCKKDM4EALDH1A1HPGD | |
| SCHEMBL18934523 | 0.78 | KMT2A (0.44) | KMT2ALCKKDM4EALDH1A1HPGD | |
| SCHEMBL23903174 | 0.77 | APAF1 (0.44) | MAPK10MAPK8MAPK14KMT2AAURKA | |
| SCHEMBL18934626 | 0.76 | KMT2A (0.41) | KMT2ALCKKDM4EALDH1A1HPGD | |
| SCHEMBL1698065 | 0.73 | KDM4E (0.53) | MAPK10KMT2AKDM4EAURKAALDH1A1 | |
| SCHEMBL18934881 | 0.72 | KDM4E (0.48) | MAPK10KMT2AKDM4EAURKAALDH1A1 | |
| SCHEMBL18919880 | 0.72 | LCK (0.42) | MAPK10MAPK8MAPK14KMT2ALCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093958-A1 | BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES | IDEMITSU KOSAN CO., LTD. (JP) | 2017-06-08 | — | — | WO | disclosed |