Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CASP9 | P55211 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | PTK6 | Q13882 | 3/20 | 0.40 |
| ▸ | C1R | P00736 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18934624 | 0.85 | MAPK8 (0.41) | APAF1TDP2CDC25BCASP3CASP7 | |
| SCHEMBL18934522 | 0.79 | LCK (0.44) | APAF1TDP2CDC25BCASP3CASP7 | |
| SCHEMBL23903129 | 0.77 | CYP1A1 (0.47) | CDC25BMAPK8MAPK10NPC1ALDH1A1 | |
| SCHEMBL23902881 | 0.77 | RAB9A (0.49) | APAF1TDP2CDC25BCASP3CASP7 | |
| SCHEMBL18934883 | 0.77 | MAPK10 (0.44) | APAF1TDP2CDC25BCASP3CASP7 | |
| SCHEMBL18934627 | 0.77 | MAPK8 (0.41) | APAF1TDP2CDC25BCASP3CASP7 | |
| SCHEMBL11827448 | 0.75 | KDM4E (0.55) | CDC25BMAPK8MAPK10NPC1ALDH1A1 | |
| SCHEMBL23903106 | 0.72 | AHR (0.45) | CDC25BMAPK8MAPK10ALDH1A1SMN1; SMN2 | |
| SCHEMBL18253544 | 0.70 | MAPK8 (0.57) | APAF1TDP2CDC25BCASP3CASP7 | |
| SCHEMBL11831298 | 0.69 | POLB (0.43) | NPC1ALDH1A1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151026-A1 | MULTI-LAYER BODY FOR DIFFUSE TRANSILLUMINATION | MERCK PATENT GMBH (DE) | 2023-05-18 | — | — | US | disclosed |
| US-20230151026-A1 | MULTI-LAYER BODY FOR DIFFUSE TRANSILLUMINATION | MERCK PATENT GMBH (DE) | 2023-05-18 | — | — | US | disclosed |
| WO-2021198213-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151026-A1 | MULTI-LAYER BODY FOR DIFFUSE TRANSILLUMINATION | DDT, EPCAM, SLC18A3 | APAF1 4426/4885TDP2 464/4885CDC25B 3790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.