Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18934891 | 0.96 | KDM4E (0.41) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL18934711 | 0.88 | KDM4E (0.34) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL18934715 | 0.86 | KDM4E (0.34) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL18934619 | 0.83 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL23370434 | 0.82 | L3MBTL1 (0.50) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL12691203 | 0.82 | L3MBTL1 (0.50) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL16066567 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL16674294 | 0.81 | L3MBTL1 (0.53) | KDM4EALDH1A1HPGDGAAMAPT | |
| SCHEMBL14208656 | 0.81 | L3MBTL1 (0.49) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL17278443 | 0.81 | L3MBTL1 (0.53) | KDM4EALDH1A1HPGDGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093958-A1 | BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES | IDEMITSU KOSAN CO., LTD. (JP) | 2017-06-08 | — | — | WO | disclosed |