Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLB | Q8NCG7 | 13/20 | 0.60 |
| ▸ | DAGLA | Q9Y4D2 | 8/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18936191 | 0.90 | DAGLA (0.67) | DAGLBDAGLAROCK2 | |
| SCHEMBL18935800 | 0.82 | DAGLA (0.50) | DAGLBDAGLA | |
| SCHEMBL18921267 | 0.79 | DAGLB (0.88) | DAGLBDAGLA | |
| SCHEMBL20576801 | 0.78 | DAGLB (0.67) | DAGLBDAGLAROCK2 | |
| SCHEMBL18936720 | 0.77 | DAGLB (0.66) | DAGLBDAGLA | |
| SCHEMBL20575837 | 0.75 | DAGLB (1.00) | DAGLBDAGLA | |
| SCHEMBL18935653 | 0.75 | DAGLB (1.00) | DAGLBDAGLA | |
| SCHEMBL20575918 | 0.74 | DAGLB (1.00) | DAGLBDAGLA | |
| SCHEMBL18936596 | 0.73 | DAGLB (1.00) | DAGLBDAGLA | |
| SCHEMBL20576109 | 0.72 | DAGLB (1.00) | DAGLBDAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017096315-A1 | TRIAZOLE DAGL(α) INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-06-08 | — | — | WO | disclosed |