Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLB | Q8NCG7 | 9/20 | 0.66 |
| ▸ | DAGLA | Q9Y4D2 | 15/20 | 0.52 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18935800 | 0.83 | DAGLA (0.50) | DAGLBDAGLAABHD6 | |
| SCHEMBL18936608 | 0.79 | DAGLB (1.00) | DAGLBDAGLAABHD6 | |
| SCHEMBL18935808 | 0.77 | DAGLB (0.60) | DAGLBDAGLA | |
| SCHEMBL18936191 | 0.77 | DAGLA (0.67) | DAGLBDAGLA | |
| SCHEMBL20575411 | 0.69 | DAGLA (1.00) | DAGLBDAGLAABHD6 | |
| SCHEMBL15426530 | 0.66 | DAGLA (0.80) | DAGLBDAGLAABHD6 | |
| SCHEMBL21138521 | 0.66 | HSD11B1 (0.62) | DAGLBDAGLAABHD6 | |
| SCHEMBL27651068 | 0.66 | HSD11B1 (0.58) | DAGLBDAGLAABHD6 | |
| SCHEMBL20576033 | 0.66 | DAGLA (0.46) | DAGLBDAGLAABHD6 | |
| SCHEMBL20575923 | 0.66 | DAGLA (1.00) | DAGLBDAGLAABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017096315-A1 | TRIAZOLE DAGL(α) INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-06-08 | — | — | WO | disclosed |