SCHEMBL189361

SCHEMBL189361

CNC1CCN(C(=O)OC(C)(C)C)C1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.57
USP30 Q70CQ3 6/20 0.50
ALDH1A1 P00352 3/20 0.50
HSD11B1 P28845 2/20 0.50
CYP2C9 P11712 1/20 0.50
MAPT P10636 2/20 0.49
NPC1 O15118 1/20 0.49
MAPK1 P28482 1/20 0.49
HTT P42858 1/20 0.49
RAB9A P51151 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
HPGD P15428 1/20 0.49
RECQL P46063 1/20 0.47
PTPN2 P17706 1/20 0.46
PTPN1 P18031 1/20 0.46
PTPN6 P29350 1/20 0.46
USP2 O75604 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL671402 1.00 EPHX1 (0.57) EPHX1USP30ALDH1A1HSD11B1CYP2C9
SCHEMBL2500606 1.00 EPHX1 (0.57) EPHX1USP30ALDH1A1HSD11B1CYP2C9
Hydrochloric Acid SCHEMBL2500609 0.98 EPHX1 (0.56) EPHX1USP30ALDH1A1HSD11B1CYP2C9
Hydrochloric Acid SCHEMBL2495441 0.98 EPHX1 (0.56) EPHX1USP30ALDH1A1HSD11B1CYP2C9
SCHEMBL2026360 0.90 EPHX1 (0.55) EPHX1USP30ALDH1A1HSD11B1CYP2C9
SCHEMBL556321 0.90 EPHX1 (0.55) EPHX1USP30ALDH1A1HSD11B1CYP2C9
SCHEMBL2024838 0.90 EPHX1 (0.55) EPHX1USP30ALDH1A1HSD11B1CYP2C9
SCHEMBL215297 0.90 EPHX1 (0.65) EPHX1ALDH1A1MAPTNPC1MAPK1
SCHEMBL2069710 0.89 EPHX1 (0.57) EPHX1USP30ALDH1A1HSD11B1CYP2C9
SCHEMBL6758420 0.89 EPHX1 (0.57) EPHX1USP30ALDH1A1HSD11B1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 368 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106630205-A Anti-scale inhibitor for treating industrial circulating water 安徽省蓝天能源环保科技有限公司 2017-05-10 CN claimed
US-12637426-B2 1-cyano-pyrrolidine compounds as USP30 inhibitors MISSION THERAPEUTICS LIMITED (GB) 2026-05-26 US disclosed
US-12528818-B2 Compositions and methods for inhibition of RAS LEIDOS BIOMEDICAL RESEARCH, INC. (US) 2026-01-20 US disclosed
EP-4370207-B1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2025-12-17 EP disclosed
EP-4139299-B1 KRAS G12D PROTEIN INHIBITORS TAIHO PHARMACEUTICAL CO LTD (JP) 2025-12-17 EP disclosed
US-20250340548-A1 KRAS G12C INHIBITORS FRONTIER MEDICINES CORP (US) 2025-11-06 US disclosed
US-12448368-B2 Indole compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2025-10-21 US disclosed
US-20250289814-A1 COMPOUNDS AS PARP1 INHIBITIORS NINGBO NEWBAY TECH DEVELOPMENT CO LTD (CN) 2025-09-18 US disclosed
US-20250270225-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF RAS NNSA 2025-08-28 US disclosed
US-12291539-B2 KRAS G12C inhibitors FRONTIER MEDICINES CORPORATION (US) 2025-05-06 US disclosed
US-20060247226-A1 XANTHINE DERIVATIVES, THE PREPARATION THEREOF AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS HIMMELSBACH FRANK 2006-11-02 US disclosed
US-20060205711-A1 Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2006-09-14 US disclosed
WO-2005047293-A1 MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISTS AND COMPOSITIONS AND METHODS RELATED THERETO NEUROCRINE BIOSCIENCES, INC. (US) 2005-05-26 WO disclosed
US-20040242888-A1 Process for producing 1-alkoxycarbonyl nitrogenous saturated heterocyclic derivative TORAY FINE CHEMICALS CO., LTD., A CORPORATION OF JAPAN (JP) 2004-12-02 US disclosed
EP-1460061-A1 PROCESS FOR PRODUCING 1-ALKOXYCARBONYL NITROGENOUS SATURATED HETEROCYCLIC DERIVATIVE Toray Fine Chemicals Co., Ltd. (JP) 2004-09-22 EP disclosed
US-20040147545-A1 Derivatives of oxazolidinones as antibacterial agents LABORATORIOS VITA, S.A. (ES) 2004-07-29 US disclosed
US-20040087587-A1 Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2004-05-06 US disclosed
US-20040077645-A1 Dipeptidyl aminopeptidase inhibitors; diabetes mellitus, arthritis, obesity, allograft transplantation and osteoporosis treatment BOEHRINGER INGELHEIM PHARMA GMBH & CO KG (DE) 2004-04-22 US disclosed
US-20020198205-A1 Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-12-26 US disclosed
US-6140347-A Azetidine, pyrrolidine and piperidine derivatives as 5-HT receptor agonists MERCK SHARP & DOHME LTD. (GB) 2000-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040242888-A1 Process for producing 1-alkoxycarbonyl nitrogenous saturated heterocyclic derivative DAO, DDO, ODC1 EPHX1 2315/4885USP30 2643/4885ALDH1A1 2193/4885
US-20040087587-A1 Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions DPP4, DPP3, DPP7 EPHX1 919/4885USP30 2578/4885ALDH1A1 187/4885
US-20250270225-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF RAS KRAS, NRAS, HRAS EPHX1 697/4885USP30 1258/4885ALDH1A1 3077/4885
US-20250289814-A1 COMPOUNDS AS PARP1 INHIBITIORS PARP1, PARP11, PARP12 EPHX1 4480/4885USP30 1745/4885ALDH1A1 434/4885
US-20060205711-A1 Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions DPP4, DPP3, DPP7 EPHX1 837/4885USP30 2353/4885ALDH1A1 238/4885
US-20060247226-A1 XANTHINE DERIVATIVES, THE PREPARATION THEREOF AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS DPP4, DPP3, DPP7 EPHX1 837/4885USP30 2353/4885ALDH1A1 238/4885
US-12291539-B2 KRAS G12C inhibitors KRAS, NRAS, HRAS EPHX1 1898/4885USP30 1382/4885ALDH1A1 3319/4885
US-20250340548-A1 KRAS G12C INHIBITORS KRAS, NRAS, HRAS EPHX1 1898/4885USP30 1382/4885ALDH1A1 3319/4885
US-12637426-B2 1-cyano-pyrrolidine compounds as USP30 inhibitors USP30, USP1, USP10 EPHX1 3856/4885USP30 1/4885ALDH1A1 1185/4885
US-12448368-B2 Indole compounds as androgen receptor modulators AR, FSHR, ADRB3 EPHX1 4776/4885USP30 2794/4885ALDH1A1 2697/4885
US-20020198205-A1 Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions DPP4, DPP3, DPP7 EPHX1 919/4885USP30 2578/4885ALDH1A1 187/4885
US-12528818-B2 Compositions and methods for inhibition of RAS KRAS, NRAS, HRAS EPHX1 1925/4885USP30 1723/4885ALDH1A1 2644/4885
US-20040077645-A1 Dipeptidyl aminopeptidase inhibitors; diabetes mellitus, arthritis, obesity, allograft transplantation and osteoporosis treatment DPP4, DPP3, DPP7 EPHX1 1997/4885USP30 2621/4885ALDH1A1 178/4885
US-20040147545-A1 Derivatives of oxazolidinones as antibacterial agents OXA1L, Q6ZSR9, PGC EPHX1 2356/4885USP30 4108/4885ALDH1A1 1970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.