Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.48 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.48 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.48 |
| ▸ | BDNF | P23560 | 3/20 | 0.45 |
| ▸ | MDK | P21741 | 3/20 | 0.45 |
| ▸ | PTN | P21246 | 2/20 | 0.45 |
| ▸ | BMP2 | P12643 | 2/20 | 0.41 |
| ▸ | VEGFA | P15692 | 2/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.41 |
| ▸ | SHH | Q15465 | 2/20 | 0.41 |
| ▸ | IFNG | P01579 | 1/20 | 0.40 |
| ▸ | PF4 | P02776 | 1/20 | 0.40 |
| ▸ | CCL2 | P13500 | 1/20 | 0.40 |
| ▸ | SELP | P16109 | 1/20 | 0.40 |
| ▸ | BMP6 | P22004 | 1/20 | 0.40 |
| ▸ | CCL11 | P51671 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | SELPLG | Q14242 | 1/20 | 0.40 |
| ▸ | SELL | P14151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19731923 | 0.91 | LGALS3 (0.48) | MAPK1LGALS3LGALS8LGALS4BDNF | |
| SCHEMBL15215584 | 0.86 | MAPK1 (0.44) | MAPK1LGALS3LGALS8LGALS4BDNF | |
| SCHEMBL12213976 | 0.86 | MAPK1 (0.44) | MAPK1LGALS3LGALS8LGALS4BDNF | |
| SCHEMBL15274904 | 0.86 | MAPK1 (0.44) | MAPK1LGALS3LGALS8LGALS4BDNF | |
| SCHEMBL4544701 | 0.86 | MAPK1 (0.44) | MAPK1LGALS3LGALS8LGALS4BDNF | |
| SCHEMBL25121361 | 0.86 | MAPK1 (0.44) | MAPK1LGALS3LGALS8LGALS4BDNF | |
| SCHEMBL18254178 | 0.86 | MAPK1 (0.44) | MAPK1LGALS3LGALS8LGALS4BDNF | |
| SCHEMBL12085239 | 0.86 | MAPK1 (0.44) | MAPK1LGALS3LGALS8LGALS4BDNF | |
| SCHEMBL21374694 | 0.86 | MAPK1 (0.44) | MAPK1LGALS3LGALS8LGALS4BDNF | |
| SCHEMBL15082697 | 0.86 | MAPK1 (0.44) | MAPK1LGALS3LGALS8LGALS4BDNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170160289-A1 | SYNERGISTIC COMBINATION OF BIOMARKERS FOR DETECTING AND ASSESSING HEPATIC FIBROSIS | BIO-RAD INNOVATIONS (FR) | 2017-06-08 | — | — | US | disclosed |