SCHEMBL12085239

SCHEMBL12085239

CO[C@@H]1C(C(=O)O)O[C@@H](OC2C(NC(C)=O)C(C)OC(CO)[C@H]2O)C(O)C1O

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 2/20 0.44
▸ LGALS3 P17931 6/20 0.44
▸ LGALS8 O00214 2/20 0.44
▸ LGALS4 P56470 1/20 0.44
▸ MDK P21741 3/20 0.43
▸ BDNF P23560 3/20 0.43
▸ PTN P21246 2/20 0.43
▸ CD69 Q07108 1/20 0.41
▸ LGALS1 P09382 1/20 0.41
▸ LGALS7; LGALS7B P47929 1/20 0.41
▸ LGALS9 O00182 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ THRB P10828 1/20 0.40
▸ F10 P00742 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12952583 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL15274904 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL12213976 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL15215584 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL18254178 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL25121361 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL15082697 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL4544701 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL21374694 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL10157433 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230218500-A1 SKIN EXTERNAL COMPOSITION COMPRISING CROSSLINKED HYALURONIC ACID GEL AMOREPACIFIC CORPORATION (KR) 2023-07-13 — — US disclosed
US-20230133656-A1 HYDROGEL COMPOSITIONS AND USES THEREOF SHOICHET, MOLLY SANDRA (CA) 2023-05-04 — — US disclosed
US-11173106-B2 Compositions comprising a superhydrophilic amphiphilic copolymer and a micellar thickener JOHNSON & JOHNSON CONSUMER INC. (US) 2021-11-16 — — US disclosed
US-9937118-B2 Clear suspending personal care cleansing compositions JOHNSON & JOHNSON CONSUMER INC. (US) 2018-04-10 — — US disclosed
US-20170360680-A1 CLEAR SUSPENDING PERSONAL CARE CLEANSING COMPOSITIONS KENVUE BRANDS LLC 2017-12-21 — — US disclosed
US-20170202982-A1 Hyaluronic Acid-Based Nanoparticles as Biosensors for Imaging-Guided Surgery and Drug Delivery Vehicles and Methods Associated Therewith WAKE FOREST UNIVERSITY 2017-07-20 — — US disclosed
US-20170079893-A1 PHASE-STABLE SUNSCREEN COMPOSITIONS COMPRISING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS JOHNSON & JOHNSON CONSUMER INC. 2017-03-23 — — US disclosed
US-20120316099-A1 COMPOSITIONS COMPRISING SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND METHODS OF USE THEREOF KENVUE BRANDS LLC 2012-12-13 — — US disclosed
US-8258250-B2 Compositions comprising superhydrophilic amphiphilic copolymers and methods of use thereof JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2012-09-04 — — US disclosed
US-20110082105-A1 COMPOSITIONS COMPRISING SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND METHODS OF USE THEREOF KENVUE BRANDS LLC 2011-04-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230133656-A1 HYDROGEL COMPOSITIONS AND USES THEREOF CD44, UACA, ALDH1A2 MAPK1 3667/4885LGALS3 78/4885LGALS8 381/4885
US-20170079893-A1 PHASE-STABLE SUNSCREEN COMPOSITIONS COMPRISING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS PCNA, MMS19, SUN2 MAPK1 4401/4885LGALS3 4450/4885LGALS8 4434/4885
US-20170202982-A1 Hyaluronic Acid-Based Nanoparticles as Biosensors for Imaging-Guided Surgery and Drug Delivery Vehicles and Methods Associated Therewith CD44, HLA-A, HLA-C MAPK1 2043/4885LGALS3 15/4885LGALS8 24/4885
US-20110082105-A1 COMPOSITIONS COMPRISING SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND METHODS OF USE THEREOF PHOSPHO1, LIPA, ABHD16A MAPK1 4875/4885LGALS3 1251/4885LGALS8 1607/4885
US-20230218500-A1 SKIN EXTERNAL COMPOSITION COMPRISING CROSSLINKED HYALURONIC ACID GEL DSG1, H1-0, CD44 MAPK1 2375/4885LGALS3 1898/4885LGALS8 142/4885
US-20170360680-A1 CLEAR SUSPENDING PERSONAL CARE CLEANSING COMPOSITIONS DSG1, CUTA, SNU13 MAPK1 3782/4885LGALS3 1365/4885LGALS8 2170/4885
US-11173106-B2 Compositions comprising a superhydrophilic amphiphilic copolymer and a micellar thickener ABHD16A, DSG1, CUTA MAPK1 4623/4885LGALS3 1153/4885LGALS8 1224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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