Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 9/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15243054 | 0.85 | PTGER2 (0.35) | PKMPTGER2PTGDR2FFAR1 | |
| SCHEMBL6744367 | 0.84 | PKM (0.53) | PKMTDP1PTGER2TSHRPOLB | |
| SCHEMBL14774855 | 0.81 | ALDH1A1 (0.47) | TDP1POLBSMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL201279 | 0.80 | PKM (0.46) | PKMTDP1PTGER2TSHRPOLB | |
| SCHEMBL14784683 | 0.80 | MAPT (0.44) | TDP1PTGER2TSHRPOLBL3MBTL1 | |
| SCHEMBL15964828 | 0.79 | PTGER2 (0.42) | PKMPTGER2POLBSMN1; SMN2GLA | |
| SCHEMBL4405598 | 0.76 | ALDH1A1 (0.45) | TDP1TSHRPOLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL7963576 | 0.75 | TDP1 (0.54) | PKMTDP1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL22601790 | 0.74 | TDP1 (0.57) | PKMTDP1PTGER2TSHRGLA | |
| SCHEMBL28662404 | 0.73 | MEN1 (0.35) | PKML3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2755944-B1 | BIARYLDERIVATIVES,THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI SA (FR) | 2017-06-14 | — | — | EP | claimed |