Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CASP6 | P55212 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP4 | P49662 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP9 | P55211 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30806655 | 0.85 | TERT (0.43) | TERTMAPTKMT2ACASP6MEN1 | |
| SCHEMBL3042096 | 0.82 | TERT (0.51) | TERTCASP6POLBAPEX1CTDSP1 | |
| SCHEMBL30806340 | 0.81 | TERT (0.47) | TERTMAPTKMT2AMEN1POLB | |
| SCHEMBL27378076 | 0.81 | TERT (0.42) | TERTMAPTKMT2AMEN1POLB | |
| SCHEMBL30806457 | 0.79 | SLC5A1 (0.40) | TERTMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL16601585 | 0.79 | HTT (0.45) | TERTMAPTKMT2AMEN1POLB | |
| SCHEMBL8130592 | 0.78 | TERT (0.48) | TERTMAPTKMT2ACASP6MEN1 | |
| SCHEMBL30806720 | 0.78 | KCNN4 (0.45) | TERT | |
| SCHEMBL13340948 | 0.77 | MAOB (0.38) | MAPTPOLBHPGDHTTSMN1; SMN2 | |
| SCHEMBL30921780 | 0.77 | PIK3CD (0.46) | KMT2ACASP6MEN1GAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093545-A1 | ANTI-BACTERIAL COMPOUNDS BASED ON AMINO-GOLD PHOSPHINE COMPLEXES | AUSPHERIX LIMITED (GB) | 2017-06-08 | — | — | WO | disclosed |