Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11508620 | 0.85 | TP53 (0.41) | KDM4ETP53 | |
| SCHEMBL22505760 | 0.78 | TP53 (0.35) | KDM4ETP53 | |
| SCHEMBL20016953 | 0.78 | TP53 (0.35) | KDM4ETP53 | |
| SCHEMBL25878482 | 0.78 | SIGMAR1 (0.35) | SIGMAR1 | |
| SCHEMBL22908524 | 0.78 | — | — | |
| SCHEMBL332013 | 0.78 | — | — | |
| SCHEMBL21029496 | 0.76 | TSHR (0.46) | KDM4ETP53 | |
| SCHEMBL330817 | 0.75 | CYP2C19 (0.41) | SIGMAR1KDM4ETP53 | |
| SCHEMBL13679247 | 0.75 | — | — | |
| SCHEMBL7649165 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751564-B1 | METHODS OF TRIGGERING ACTIVATION OF ENCAPSULATED SIGNAL-GENERATING SUBSTANCES | JUPITER DIAGNOSTICS HOLDING COMPANY LTD (GB) | 2017-06-07 | — | — | EP | disclosed |