Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
| ▸ | HTR1A | P08908 | 4/20 | 0.60 |
| ▸ | HTR7 | P34969 | 3/20 | 0.60 |
| ▸ | HTR2A | P28223 | 2/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11209809 | 0.98 | DRD2 (0.79) | DRD2HSD17B10HTR1AHTR7HTR2A | |
| SCHEMBL16303868 | 0.95 | DRD2 (0.79) | DRD2HSD17B10HTR1AHTR7HTR2A | |
| SCHEMBL5915124 | 0.90 | DRD2 (1.00) | DRD2HSD17B10HTR1AHTR7HTR2A | |
| Hydrochloric Acid SCHEMBL11218267 | 0.89 | DRD2 (0.97) | DRD2HSD17B10HTR1AHTR7HTR2A | |
| SCHEMBL10994325 | 0.86 | HSD17B10 (0.73) | DRD2HSD17B10HTR1AHTR7HTR2A | |
| SCHEMBL17124880 | 0.86 | DRD2 (0.60) | DRD2HSD17B10HTR1AHTR2AKDM4E | |
| SCHEMBL11354876 | 0.86 | HSD17B10 (1.00) | DRD2HSD17B10HTR1AHTR7HTR2A | |
| Hydrochloric Acid SCHEMBL11639840 | 0.86 | HSD17B10 (0.73) | DRD2HSD17B10HTR1AHTR7HTR2A | |
| SCHEMBL3148729 | 0.86 | HSD17B10 (0.73) | DRD2HSD17B10HTR1AHTR7HTR2A | |
| SCHEMBL18937539 | 0.86 | DRD2 (0.60) | DRD2HSD17B10HTR1AHTR2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118313-A1 | IMIDAZO [1,2-C] QUINAZOLIN-5-AMINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES | MERCK SHARP & DOHME CORP. (US) | 2019-06-20 | — | — | WO | disclosed |
| EP-2925721-B1 | S1P AND/OR ATX MODULATING AGENTS | BIOGEN MA INC (US) | 2017-06-07 | — | — | EP | disclosed |