Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18936739 | 0.87 | SIGMAR1 (0.66) | SIGMAR1PARP1MEN1KMT2APPARG | |
| SCHEMBL8575395 | 0.84 | SIGMAR1 (0.62) | SIGMAR1PARP1MEN1KMT2ADRD2 | |
| SCHEMBL11938943 | 0.81 | SIGMAR1 (0.65) | SIGMAR1PPARGPPARAHTR6DRD2 | |
| SCHEMBL14601668 | 0.81 | SIGMAR1 (0.60) | SIGMAR1 | |
| SCHEMBL18937725 | 0.78 | SIGMAR1 (0.45) | SIGMAR1PPARGPPARAS1PR1S1PR3 | |
| SCHEMBL10254250 | 0.77 | SIGMAR1 (0.52) | SIGMAR1HTR6 | |
| SCHEMBL14438052 | 0.77 | PPARG (0.51) | SIGMAR1MEN1KMT2APPARGPPARA | |
| SCHEMBL4237702 | 0.77 | SIGMAR1 (0.54) | SIGMAR1KMT2ADRD2 | |
| SCHEMBL256663 | 0.77 | SIGMAR1 (0.63) | SIGMAR1PARP1 | |
| SCHEMBL18937710 | 0.76 | SIGMAR1 (0.43) | SIGMAR1PARP1PPARGPPARAS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925721-B1 | S1P AND/OR ATX MODULATING AGENTS | BIOGEN MA INC (US) | 2017-06-07 | — | — | EP | disclosed |