Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.66 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18937726 | 0.87 | SIGMAR1 (0.52) | SIGMAR1PARP1MEN1KMT2APPARG | |
| SCHEMBL5536604 | 0.87 | SIGMAR1 (0.65) | SIGMAR1PARP1MEN1KMT2APPARG | |
| SCHEMBL5541688 | 0.86 | SIGMAR1 (0.67) | SIGMAR1PARP1MEN1KMT2APPARG | |
| SCHEMBL5539408 | 0.85 | SIGMAR1 (0.62) | SIGMAR1PARP1MEN1KMT2APPARG | |
| SCHEMBL5536761 | 0.85 | SIGMAR1 (0.65) | SIGMAR1PARP1MEN1KMT2APPARG | |
| SCHEMBL11823875 | 0.84 | SIGMAR1 (0.60) | SIGMAR1PARP1MEN1KMT2APPARG | |
| SCHEMBL7306525 | 0.84 | SIGMAR1 (0.61) | SIGMAR1PARP1MEN1KMT2AHTR1A | |
| SCHEMBL6367251 | 0.84 | SIGMAR1 (0.61) | SIGMAR1PARP1MEN1KMT2APPARG | |
| Hydrochloric Acid SCHEMBL29662083 | 0.84 | SIGMAR1 (0.56) | SIGMAR1PARP1MEN1KMT2APPARG | |
| SCHEMBL8575395 | 0.82 | SIGMAR1 (0.62) | SIGMAR1PARP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925721-B1 | S1P AND/OR ATX MODULATING AGENTS | BIOGEN MA INC (US) | 2017-06-07 | — | — | EP | disclosed |