Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.34 |
| ▸ | GRM6 | O15303 | 2/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5473187 | 0.63 | GRM2 (0.42) | GRM5GRM2GRM1GRM6GRM4 | |
| SCHEMBL1595374 | 0.63 | GRM1 (0.37) | GRM5GRM2GRM1GRM6GRM4 | |
| SCHEMBL6062768 | 0.61 | GRM1 (0.36) | GRM5GRM2GRM1GRM6GRM4 | |
| SCHEMBL12420565 | 0.60 | GRM2 (0.35) | GRM5GRM2GRM1GRM6GRM4 | |
| SCHEMBL1923010 | 0.60 | GRM2 (0.35) | GRM5GRM2GRM1GRM6GRM4 | |
| SCHEMBL10614719 | 0.59 | APLNR (0.39) | GRM5GRM2GRM1GRM6GRM4 | |
| SCHEMBL3683146 | 0.57 | POLB (0.43) | GRM5GRM2GRM1GRM6GRM4 | |
| SCHEMBL12226905 | 0.57 | POLB (0.48) | GRM2GRM1POLBAPEX1TDP1 | |
| SCHEMBL967161 | 0.57 | POLB (0.48) | GRM5GRM2GRM1GRM6GRM4 | |
| SCHEMBL1664043 | 0.57 | POLB (0.48) | GRM2GRM1POLBAPEX1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105690-A1 | Method for Making Propylene Impact Copolymers with Balanced Impact Strength and Stiffness | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-05-05 | — | — | US | disclosed |