SCHEMBL3683146

SCHEMBL3683146

O=C(O)C1C2CC(C2)C1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.43
TDP1 Q9NUW8 3/20 0.43
LMNA P02545 4/20 0.41
PMP22 Q01453 2/20 0.41
TSHR P16473 2/20 0.41
APEX1 P27695 1/20 0.41
KDM4E B2RXH2 1/20 0.41
GMNN O75496 1/20 0.41
TFPI2 P48307 1/20 0.41
TP53 P04637 1/20 0.41
NFKB1 P19838 1/20 0.41
THPO P40225 1/20 0.41
CYP2D6 P10635 2/20 0.40
BLM P54132 2/20 0.40
KMT2A Q03164 2/20 0.40
ALOX15 P16050 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
RAB9A P51151 1/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29099215 0.93 POLB (0.43) POLBTDP1LMNAPMP22TSHR
SCHEMBL1536316 0.93
SCHEMBL12576169 0.88 KMT2A (0.42) POLBTDP1LMNAPMP22TSHR
SCHEMBL14433686 0.87 LMNA (0.52) POLBTDP1LMNAPMP22TSHR
SCHEMBL1004125 0.87 LMNA (0.52) POLBTDP1LMNAPMP22TSHR
SCHEMBL23698034 0.87 LMNA (0.52) POLBTDP1LMNAPMP22TSHR
SCHEMBL3045980 0.87 LMNA (0.52) POLBTDP1LMNAPMP22TSHR
SCHEMBL3031493 0.87 LMNA (0.52) POLBTDP1LMNAPMP22TSHR
SCHEMBL23176525 0.87 LMNA (0.52) POLBTDP1LMNAPMP22TSHR
SCHEMBL187221 0.87 LMNA (0.52) POLBTDP1LMNAPMP22TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9403956-B2 Incipient wetness method to enhance productivity of supported Ziegler-Natta catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-08-02 US disclosed
EP-2953986-A1 INCIPIENT WETNESS METHOD TO ENHANCE PRODUCTIVITY OF SUPPORTED ZIEGLER-NATTA CATALYSTS ExxonMobil Chemical Patents Inc. (US) 2015-12-16 EP disclosed
US-9000106-B2 Copolymer production system and process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-04-07 US disclosed
WO-2014123684-A1 INCIPIENT WETNESS METHOD TO ENHANCE PRODUCTIVITY OF SUPPORTED ZIEGLER-NATTA CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-08-14 WO disclosed
US-20140221515-A1 Incipient Wetness Method to Enhance Productivity of Supported Ziegler-Natta Catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2014-08-07 US disclosed
US-20130296506-A1 Copolymer Production System and Process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-11-07 US disclosed
US-8076419-B2 Method for making propylene impact copolymers with balanced impact strength and stiffness EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-12-13 US disclosed
US-7851554-B2 Propylene impact copolymers with balanced impact strength and stiffness EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-12-14 US disclosed
US-20100105848-A1 Propylene Impact Copolymers With Balanced Impact Strength And Stiffness EXXONMOBIL CHEMICAL PATENTS INC. 2010-04-29 US disclosed