Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679607 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL413228 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL18934846 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL13060381 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL6917808 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL24618011 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL1678569 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL18935496 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL21212072 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| Hydrochloric Acid SCHEMBL7274485 | 0.97 | HDAC8 (0.58) | HDAC8HDAC6EPHX1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230108803-A1 | ANTIVIRAL HETEROCYCLIC COMPOUNDS | ENANTA PHARMACEUTICALS, INC. | 2023-04-06 | — | — | US | disclosed |
| US-11420976-B2 | Heterocyclic compounds as anti-viral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| US-20220205992-A1 | MATERIALS AND KITS RELATING TO ASSOCIATION OF REPORTER SPECIES AND TARGETING ENTITIES WITH BEADS | Quanterix Corporation (US) | 2022-06-30 | — | — | US | disclosed |
| US-20210238188-A1 | HETEROCYCLIC COMPOUNDS AS ANTI-VIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2021-08-05 | — | — | US | disclosed |
| US-20200362089-A1 | ARTICLE | DAIKIN AMERICA, INC. (US) | 2020-11-19 | — | — | US | disclosed |
| US-20170240704-A1 | SILANE ENDCAPPED POLYAMIDE RESINS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2017-08-24 | — | — | US | disclosed |
| WO-2017096045-A1 | MULTIVALENT RAS BINDING COMPOUNDS | KYRAS THERAPEUTICS, INC. (US) | 2017-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238188-A1 | HETEROCYCLIC COMPOUNDS AS ANTI-VIRAL AGENTS | VIP, ACE, FURIN | HDAC8 464/4885HDAC6 251/4885EPHX1 446/4885 |
| US-20170240704-A1 | SILANE ENDCAPPED POLYAMIDE RESINS | FFAR3, FFAR2, FFAR1 | HDAC8 1704/4885HDAC6 2881/4885EPHX1 1732/4885 |
| US-11420976-B2 | Heterocyclic compounds as anti-viral agents | VIP, ACE, FURIN | HDAC8 464/4885HDAC6 251/4885EPHX1 446/4885 |
| US-20230108803-A1 | ANTIVIRAL HETEROCYCLIC COMPOUNDS | ACE, HPRT1, ACE2 | HDAC8 1283/4885HDAC6 690/4885EPHX1 224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.